Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | mazEF/MazF(toxin) |
Location | 846568..847092 | Replicon | chromosome |
Accession | NZ_CP094713 | ||
Organism | Staphylococcus schleiferi strain IVB6180 |
Toxin (Protein)
Gene name | mazF | Uniprot ID | S2X8B9 |
Locus tag | MUA91_RS03810 | Protein ID | WP_016426488.1 |
Coordinates | 846739..847092 (+) | Length | 118 a.a. |
Antitoxin (Protein)
Gene name | mazE | Uniprot ID | S2XCM0 |
Locus tag | MUA91_RS03805 | Protein ID | WP_016426487.1 |
Coordinates | 846568..846738 (+) | Length | 57 a.a. |
Genomic Context
Location: 842496..842924 (429 bp)
Type: Others
Protein ID: WP_167512901.1
Type: Others
Protein ID: WP_167512901.1
Location: 842917..844431 (1515 bp)
Type: Others
Protein ID: WP_155976489.1
Type: Others
Protein ID: WP_155976489.1
Location: 844415..844936 (522 bp)
Type: Others
Protein ID: WP_126496614.1
Type: Others
Protein ID: WP_126496614.1
Location: 844933..845289 (357 bp)
Type: Others
Protein ID: WP_016426485.1
Type: Others
Protein ID: WP_016426485.1
Location: 845334..846482 (1149 bp)
Type: Others
Protein ID: WP_262569915.1
Type: Others
Protein ID: WP_262569915.1
Location: 846568..846738 (171 bp)
Type: Antitoxin
Protein ID: WP_016426487.1
Type: Antitoxin
Protein ID: WP_016426487.1
Location: 846739..847092 (354 bp)
Type: Toxin
Protein ID: WP_016426488.1
Type: Toxin
Protein ID: WP_016426488.1
Location: 847151..848155 (1005 bp)
Type: Others
Protein ID: WP_262569916.1
Type: Others
Protein ID: WP_262569916.1
Location: 848234..848560 (327 bp)
Type: Others
Protein ID: WP_016426490.1
Type: Others
Protein ID: WP_016426490.1
Location: 848562..849041 (480 bp)
Type: Others
Protein ID: WP_167732819.1
Type: Others
Protein ID: WP_167732819.1
Location: 849016..849786 (771 bp)
Type: Others
Protein ID: WP_016426492.1
Type: Others
Protein ID: WP_016426492.1
Location: 850373..851578 (1206 bp)
Type: Others
Protein ID: WP_081635139.1
Type: Others
Protein ID: WP_081635139.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
MUA91_RS03780 (MUA91_03770) | 842496..842924 | + | 429 | WP_167512901.1 | PH domain-containing protein | - |
MUA91_RS03785 (MUA91_03775) | 842917..844431 | + | 1515 | WP_155976489.1 | PH domain-containing protein | - |
MUA91_RS03790 (MUA91_03780) | 844415..844936 | + | 522 | WP_126496614.1 | PH domain-containing protein | - |
MUA91_RS03795 (MUA91_03785) | 844933..845289 | + | 357 | WP_016426485.1 | holo-ACP synthase | - |
MUA91_RS03800 (MUA91_03790) | 845334..846482 | + | 1149 | WP_262569915.1 | alanine racemase | - |
MUA91_RS03805 (MUA91_03795) | 846568..846738 | + | 171 | WP_016426487.1 | type II toxin-antitoxin system antitoxin MazE | Antitoxin |
MUA91_RS03810 (MUA91_03800) | 846739..847092 | + | 354 | WP_016426488.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin |
MUA91_RS03815 (MUA91_03805) | 847151..848155 | + | 1005 | WP_262569916.1 | PP2C family protein-serine/threonine phosphatase | - |
MUA91_RS03820 (MUA91_03810) | 848234..848560 | + | 327 | WP_016426490.1 | anti-sigma factor antagonist | - |
MUA91_RS03825 (MUA91_03815) | 848562..849041 | + | 480 | WP_167732819.1 | anti-sigma B factor RsbW | - |
MUA91_RS03830 (MUA91_03820) | 849016..849786 | + | 771 | WP_016426492.1 | RNA polymerase sigma factor SigB | - |
MUA91_RS03835 (MUA91_03825) | 850373..851578 | - | 1206 | WP_081635139.1 | IS110 family transposase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 118 a.a. Molecular weight: 13157.33 Da Isoelectric Point: 10.1660
>T240038 WP_016426488.1 NZ_CP094713:846739-847092 [Staphylococcus schleiferi]
MKRGDVYLADLSPVQGSEQGGVRPVVIIQNDTGNKYSPTVIVAAITGRINKAKIPTHVEIEKNKYKLDKDSVILLEQIRT
VDKKRLKEKLTFLSEEKMKEVNYALGISLGLNMNHHK
MKRGDVYLADLSPVQGSEQGGVRPVVIIQNDTGNKYSPTVIVAAITGRINKAKIPTHVEIEKNKYKLDKDSVILLEQIRT
VDKKRLKEKLTFLSEEKMKEVNYALGISLGLNMNHHK
Download Length: 354 bp
>T240038 NZ_LS483476:736194-736544 [Lederbergia lentus]
TTGGCCGTAAAGCGTGGTGACGTGTATTTCGCCGACTTATCTCCAGTGGTCGGTTCAGAGCAAGGCGGCGTCCGGCCAGT
GCTGGTAATTCAGAATGATATTGGGAATCGTTTTAGCCCTACTGTAATTGTTGCTGCAATTACAGCACAGATACAAAAAG
CAAAACTGCCTACTCATGTGGAGATTGATTCTAAGCGTTATAGTTTTGAGAGAGACTCTGTGCTATTATTAGAACAAGTT
AGAACAATTGATAAGCAACGTTTAACAGACAAGATTACACATCTTGACGAAGAAATGATGAAAAAAGTAGATGAAGCCTT
ACAAATAAGTCTTGGACTCATCGATTTTTAA
TTGGCCGTAAAGCGTGGTGACGTGTATTTCGCCGACTTATCTCCAGTGGTCGGTTCAGAGCAAGGCGGCGTCCGGCCAGT
GCTGGTAATTCAGAATGATATTGGGAATCGTTTTAGCCCTACTGTAATTGTTGCTGCAATTACAGCACAGATACAAAAAG
CAAAACTGCCTACTCATGTGGAGATTGATTCTAAGCGTTATAGTTTTGAGAGAGACTCTGTGCTATTATTAGAACAAGTT
AGAACAATTGATAAGCAACGTTTAACAGACAAGATTACACATCTTGACGAAGAAATGATGAAAAAAGTAGATGAAGCCTT
ACAAATAAGTCTTGGACTCATCGATTTTTAA
Antitoxin
Download Length: 57 a.a. Molecular weight: 6370.00 Da Isoelectric Point: 3.9760
>AT240038 WP_016426487.1 NZ_CP094713:846568-846738 [Staphylococcus schleiferi]
MSAFNQTRFKNLEQSLKEGYVQMADLNLSLATEAYSVECEACDCNESHLLSDYKDD
MSAFNQTRFKNLEQSLKEGYVQMADLNLSLATEAYSVECEACDCNESHLLSDYKDD
Download Length: 171 bp
>AT240038 NZ_LS483476:735908-736189 [Lederbergia lentus]
GTGTCAGAATCCAGCGCAACAACAGAAATTATTATACGATTGCCGCAGCAACTTATCGCGGAAATGGATGGTTATGCAGA
GCAAGAAAATCTAAATCATAGCGAAATTATTTATCGTGCTACTAAGGTGTATCTTCGTGAGCGAAAAAAACGCCAAATCA
TTGAATCCATGAGACGCGGATATATGGAGATGGCCAAAATTAATTTGGCGATTGCATCAGAAGCTCTCCAAGCGGAATAT
GAGGCAGAAAACACAGTCGAACGGCTTGTAAGCGGAGGATAA
GTGTCAGAATCCAGCGCAACAACAGAAATTATTATACGATTGCCGCAGCAACTTATCGCGGAAATGGATGGTTATGCAGA
GCAAGAAAATCTAAATCATAGCGAAATTATTTATCGTGCTACTAAGGTGTATCTTCGTGAGCGAAAAAAACGCCAAATCA
TTGAATCCATGAGACGCGGATATATGGAGATGGCCAAAATTAATTTGGCGATTGCATCAGAAGCTCTCCAAGCGGAATAT
GAGGCAGAAAACACAGTCGAACGGCTTGTAAGCGGAGGATAA