239992

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 3901032..3901594 Replicon chromosome
Accession NZ_CP094665
Organism Gordonia amicalis strain G2

Toxin (Protein)


Gene name relE Uniprot ID A0A290XKJ4
Locus tag MTX80_RS17895 Protein ID WP_006438782.1
Coordinates 3901032..3901322 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7J5WZ76
Locus tag MTX80_RS17900 Protein ID WP_006438783.1
Coordinates 3901319..3901594 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTX80_RS17875 (MTX80_17875) 3896206..3897270 + 1065 WP_243828693.1 IS630 family transposase -
MTX80_RS17880 (MTX80_17880) 3897350..3898843 + 1494 Protein_3529 long-chain fatty acid--CoA ligase -
MTX80_RS17885 (MTX80_17885) 3899713..3900183 - 471 WP_006438780.1 hypothetical protein -
MTX80_RS17890 (MTX80_17890) 3900713..3900928 - 216 WP_236577641.1 hypothetical protein -
MTX80_RS17895 (MTX80_17895) 3901032..3901322 - 291 WP_006438782.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MTX80_RS17900 (MTX80_17900) 3901319..3901594 - 276 WP_006438783.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
MTX80_RS17905 (MTX80_17905) 3901970..3902143 + 174 WP_159405104.1 hypothetical protein -
MTX80_RS17910 (MTX80_17910) 3902140..3904590 + 2451 WP_159405105.1 AAA family ATPase -
MTX80_RS17915 (MTX80_17915) 3904662..3905813 - 1152 WP_220455652.1 Fis family transcriptional regulator -
MTX80_RS17920 (MTX80_17920) 3906119..3906484 - 366 WP_159405106.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(14-94)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10789.30 Da        Isoelectric Point: 11.1310

>T239992 WP_006438782.1 NZ_CP094665:c3901322-3901032 [Gordonia amicalis]
MSDAPTDSPAPYRVEVASPARRDLQRLPSRIVHAVIEFISGPLAGNPHRLSKPLRNDLAGLHSARRGDYRVLLRIDDPNH
TIVVVRIDHRAHAYRT

Download         Length: 291 bp

>T239992 NZ_LS483438:387775-387957 [Haemophilus influenzae]
ATGTACGAAATTCTCTTTTACAGAGACCAAAATGACATTGAGCCAGTGAAAGAGTATCTGCTATCGCTGGCTCAAAATGA
AAGCAAAGATAGTCGAATTAAACTGAATAAAATTCGAGATTATGTAATCCAAACAGCCCAACAACGCTTAAGTGAATTAA
AAGAGAGATTGAAAAATGAATAA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9740.91 Da        Isoelectric Point: 4.6221

>AT239992 WP_006438783.1 NZ_CP094665:c3901594-3901319 [Gordonia amicalis]
MTTVPLGEAKDKLSALVDSAETTHDIITITKHGKPAAVLMSADDLESLHETIYWLSRAGVRDDVATADAEYAAGHTVSID
DLRAEHGMPPK

Download         Length: 276 bp

>AT239992 NZ_LS483438:387950-388246 [Haemophilus influenzae]
ATGAATAAAATCAGCCCATTAGGTTCAAATTGGAATGAGTTTGAACAGCAAATTTTCAATGAAGAAGAAATCCGAGAAAG
TAATTTGCGTGTAGCCTTAATTAAAGAATTGATTACTTCTCGCCAGCAACTTGGGATTTCCCAAAAACAACTTGAAACCT
TAAGCGGTGTGAAGCAACCTATGATTGCACGCATTGAAAAAGGACAAACGAATCCTCAGCTTGAAACGTTGTTAAAATTG
CTCGCTCCTTTAGGGAAAACCCTGTCGATTGTGCCTCTAAGGGTAAAAAATGCCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A290XKJ4

Antitoxin

Source ID Structure
AlphaFold DB A0A7J5WZ76

References