Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 459350..460003 Replicon chromosome
Accession NZ_CP094657
Organism Acinetobacter sp. XS-4

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag MMY79_RS02275 Protein ID WP_252611690.1
Coordinates 459614..460003 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag MMY79_RS02270 Protein ID WP_252611688.1
Coordinates 459350..459607 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MMY79_RS02250 (MMY79_02250) 454861..455868 + 1008 WP_252611682.1 DNA-directed RNA polymerase subunit alpha -
MMY79_RS02255 (MMY79_02255) 455887..456264 + 378 WP_002049717.1 50S ribosomal protein L17 -
MMY79_RS02260 (MMY79_02260) 456446..457936 + 1491 WP_252611684.1 NAD(P)/FAD-dependent oxidoreductase -
MMY79_RS02265 (MMY79_02265) 457988..459160 - 1173 WP_252611686.1 acyl-CoA dehydrogenase family protein -
MMY79_RS02270 (MMY79_02270) 459350..459607 + 258 WP_252611688.1 succinate dehydrogenase assembly factor 2 Antitoxin
MMY79_RS02275 (MMY79_02275) 459614..460003 + 390 WP_252611690.1 hypothetical protein Toxin
MMY79_RS02280 (MMY79_02280) 460773..461861 + 1089 WP_111855003.1 hypothetical protein -
MMY79_RS02285 (MMY79_02285) 461945..462520 + 576 WP_252611692.1 rhombosortase -
MMY79_RS02290 (MMY79_02290) 462699..464894 + 2196 WP_252611694.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15453.64 Da        Isoelectric Point: 10.1482

>T239966 WP_252611690.1 NZ_CP094657:459614-460003 [Acinetobacter sp. XS-4]
MIKELNFELKYSRFSIIFQLFIGLSLAILLYQLLSPIWWLVALILFSISFLIFLKQSRISQIAYLDQNFWSVAYSSQKII
SRLEITKIIDYQIFMVIYFEGAPMKVAIIWFDQLSLQHWKKLKILQKLH

Download         Length: 390 bp

>T239966 NZ_LS483422:1504107-1504463 [Providencia heimbachae]
TTGACATGGAAGATAACAACAAGGCCACTTTTTGAAGCTTGGTTTGAAGAACAAAACGAAGCCGTACAAGAGGAGACACT
GTCCGTCTTGAATATTTTACGGGAGTACGGCCCTTATATTGGTCGTCCGCAAGTAGATACATTAAAGGACTCTAAGTATA
GAAATATGAAGGAGTTAAGAATTCAGGTGGGTGGTCATCCGATACGAATTTGCTTTGTATTTGACCCTATGAGGAAGGGC
GTAATATTGTGTGCGGGTAATAAAAAAGGTCATGATGAAAAACGATTTTATAGCAAACTAATTAGACTTGCAGATATGGA
GTATTCGATTTATTTAAAGGGGATATATAAAATATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10295.69 Da        Isoelectric Point: 4.3805

>AT239966 WP_252611688.1 NZ_CP094657:459350-459607 [Acinetobacter sp. XS-4]
MSDEMTLEERKVVYRARRGLKEIDVYFDPYVKNYYLQADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELREFIYKLK
QYVHG

Download         Length: 258 bp

>AT239966 NZ_LS483422:1504463-1504762 [Providencia heimbachae]
ATGGGAACTTTAGAGGAACTACTGGCTAAACGCTCGCCTGAGAGCTTAAAGCGCATTGAAGCGCGAGTGGAAGAACTCCG
TCGTGAGATAACGTTATCTAAAATGCGAGAAGAGTTAAATATCTCACAAGTACAATTGGCTGAATCACTTGGGATTAAGC
AGCCCGCAGTGGTTAAGATGGAAAAATTGGGGAATGATCCCAAACTGTCGACGATTAAGCGTTACGTAAAGGCATTAGGG
GGCGAATTATCACTTGATGTCACTCTATCAAATGGTAAAAAACTTGAGCTTCATCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References