239958

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 708451..709100 Replicon chromosome
Accession NZ_CP094555
Organism Acinetobacter sp. YH12068_T

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag MST18_RS03465 Protein ID WP_180021368.1
Coordinates 708681..709100 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag MST18_RS03460 Protein ID WP_180133931.1
Coordinates 708451..708681 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MST18_RS03445 (MST18_03445) 704458..707076 + 2619 WP_180101849.1 Fe/S-dependent 2-methylisocitrate dehydratase AcnD -
MST18_RS03450 (MST18_03450) 707230..707451 + 222 WP_180021372.1 hypothetical protein -
MST18_RS03455 (MST18_03455) 707472..708353 + 882 WP_180133930.1 hypothetical protein -
MST18_RS03460 (MST18_03460) 708451..708681 + 231 WP_180133931.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
MST18_RS03465 (MST18_03465) 708681..709100 + 420 WP_180021368.1 type II toxin-antitoxin system VapC family toxin Toxin
MST18_RS03470 (MST18_03470) 709233..709376 + 144 WP_078191132.1 zinc ribbon-containing protein -
MST18_RS03475 (MST18_03475) 709504..710079 + 576 WP_111884815.1 DUF4126 domain-containing protein -
MST18_RS03480 (MST18_03480) 710227..710718 + 492 WP_180133932.1 DUF2569 domain-containing protein -
MST18_RS03485 (MST18_03485) 710938..711147 + 210 WP_078191130.1 hypothetical protein -
MST18_RS03490 (MST18_03490) 711253..711510 + 258 WP_180133933.1 hypothetical protein -
MST18_RS03495 (MST18_03495) 712934..713392 + 459 WP_180133934.1 GIY-YIG nuclease family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-128)

Antitoxin

SpoVT-AbrB domain

(7-43)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 16191.55 Da        Isoelectric Point: 6.2194

>T239958 WP_180021368.1 NZ_CP094555:708681-709100 [Acinetobacter sp. YH12068_T]
MPTQYLLDTNICIYITKHQPEIVRQHFERHLPDGNIFISVITLGELRFGAEKSQWKDKAFKVIDELTSIIPVIELDEHTA
VHYAQIRKQLALQGQIIGNNDLWLAAHARSNNWVMVTNNEKEFLRVDELQVENWLSKSL

Download         Length: 420 bp

>T239958 NZ_LS483418:c1338519-1338259 [Streptococcus suis]
ATGTATCATTTAGAGTATTCTAAAAAGGCTCAAAAGCAAATTATGAAATTAGATAGGCAAATTCAGAGGCTGTTGTTTGC
TTGGATTGATAAACACTTAGAAGGGACTGATAATCCACGCGCCAATGGTAAAGGTTTGACAGGCAATCATGCTAACGAGT
GGCGTTATCGTATCGGAGATTACCGACTGATTTGCGATATTCAAGATGATAAGTTGGTTATTTTAGCACTTGAGTTTGGA
CATCGTAAAGATGTCTATTGA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8947.22 Da        Isoelectric Point: 4.6936

>AT239958 WP_180133931.1 NZ_CP094555:708451-708681 [Acinetobacter sp. YH12068_T]
MTTAKVFMTGRSQAIRLPKEFRFEGKEVEIFRRGDEVILREKPVTADQLFKVLAQMPDDFYAETRVDEPPQEREEV

Download         Length: 231 bp

>AT239958 NZ_LS483418:c1338742-1338521 [Streptococcus suis]
ATGAGTACAGTGACAATCAGATTAAATCAAGAAGAAGAAGTATTCTTTAAAAGCTATGCACAATTAACAGGTCAAAGTCT
TTCTAGCCTTTTTAAGAAAGCTTTGGAGCGTGATATTGAAGATGAGTATGATTTAAAAATCTATCATCAAGCTTATGATG
AGTACAAAGCAGATCCAGAAACAATTAGTCATGCTGATTTTAAGAAAGAGCTAGGATTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References