Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 456159..456795 Replicon chromosome
Accession NZ_CP094555
Organism Acinetobacter sp. YH12068_T

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag MST18_RS02255 Protein ID WP_111885419.1
Coordinates 456409..456795 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag MST18_RS02250 Protein ID WP_078189264.1
Coordinates 456159..456416 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MST18_RS02230 (MST18_02230) 451756..452121 + 366 WP_005012953.1 50S ribosomal protein L17 -
MST18_RS02235 (MST18_02235) 452338..453828 + 1491 WP_180133473.1 NAD(P)/FAD-dependent oxidoreductase -
MST18_RS02240 (MST18_02240) 453963..454760 + 798 WP_257250193.1 alpha/beta hydrolase -
MST18_RS02245 (MST18_02245) 454805..455977 - 1173 WP_180133474.1 acyl-CoA dehydrogenase family protein -
MST18_RS02250 (MST18_02250) 456159..456416 + 258 WP_078189264.1 succinate dehydrogenase assembly factor 2 Antitoxin
MST18_RS02255 (MST18_02255) 456409..456795 + 387 WP_111885419.1 hypothetical protein Toxin
MST18_RS02260 (MST18_02260) 457315..458379 + 1065 WP_180133475.1 hypothetical protein -
MST18_RS02265 (MST18_02265) 458421..458993 + 573 WP_180133476.1 rhombosortase -
MST18_RS02270 (MST18_02270) 459185..461386 + 2202 WP_180133477.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 15485.64 Da        Isoelectric Point: 10.9047

>T239957 WP_111885419.1 NZ_CP094555:456409-456795 [Acinetobacter sp. YH12068_T]
MDNRQFKLKRSFLSHAFQFFIFAVLMTLLYQLLTPMLWGIFFLIGLVVYVLFFRKHLHVTSLEYLDGTDWSLQRLNRPVQ
RVQISHILDHQMYIVVYFMHARAKPVIIWRDQLSLKQWKSLKVLAKMI

Download         Length: 387 bp

>T239957 NZ_LS483418:c847092-846835 [Streptococcus suis]
ATGAAGACCTGTTATAAACTCGTACCGACCAGTCGTTTTATTAAACAGTTGAAAAAGTTGGACAAATTTACCCAAAAACA
GATTACCAACTACTTGTCCAGTCATGTGACTGACAACCCTAGACAATACGGAAAAGCCTTGACTGCTAATCGTTCTGGCC
AATGGCGCTATCGTATCGGCAATTACAGGGTTATCGTTAATATTGAAGATGATAAATTGATTGTGACAAGCATAAAAATG
AGAAATGGAAGTATATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10126.55 Da        Isoelectric Point: 4.5716

>AT239957 WP_078189264.1 NZ_CP094555:456159-456416 [Acinetobacter sp. YH12068_T]
MTDEISLEERKVIYRARRGLKEIDVYFDPYVKNYYLQADAAEKDMFAELVAAEDPDLLDWFMEVSEPPRPELKTFIQKLK
HYVHG

Download         Length: 258 bp

>AT239957 NZ_LS483418:c847327-847076 [Streptococcus suis]
ATGGCAGCTATTACATTGAAAGTTTCTGAGCAGGACAAGCTCTTTATGCAGGCTATGGCAAAGTTTGAAGGTGTCAGTTT
GTCAGAACTCATTCGGACTAAAACCCTTGAAGCTCTCGAAGATGAATATGATGCCCGTGTGGCAGATATCGCTCTGTCTG
AATACGAGGCAGACTTGGCGAAAGGCATTGAGCCGATTAGCTGGGAGGAAATGTTGGAAGAGTTGGGGTTGACGGATGAA
GACCTGTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References