Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 723026..723675 Replicon chromosome
Accession NZ_CP094545
Organism Acinetobacter sp. YH16056_T

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag MST17_RS03515 Protein ID WP_078192327.1
Coordinates 723256..723675 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag MST17_RS03510 Protein ID WP_078191134.1
Coordinates 723026..723256 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MST17_RS03500 (MST17_03500) 719349..721967 + 2619 WP_180027260.1 Fe/S-dependent 2-methylisocitrate dehydratase AcnD -
MST17_RS03505 (MST17_03505) 722050..722958 + 909 WP_180027259.1 hypothetical protein -
MST17_RS03510 (MST17_03510) 723026..723256 + 231 WP_078191134.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
MST17_RS03515 (MST17_03515) 723256..723675 + 420 WP_078192327.1 type II toxin-antitoxin system VapC family toxin Toxin
MST17_RS03520 (MST17_03520) 723808..723951 + 144 WP_078191132.1 zinc ribbon-containing protein -
MST17_RS03525 (MST17_03525) 724079..724654 + 576 WP_111884815.1 DUF4126 domain-containing protein -
MST17_RS03530 (MST17_03530) 724847..725293 + 447 WP_180027258.1 DUF2569 domain-containing protein -
MST17_RS03535 (MST17_03535) 725511..725720 + 210 WP_078191130.1 hypothetical protein -
MST17_RS03540 (MST17_03540) 725826..726083 + 258 WP_180027257.1 hypothetical protein -
MST17_RS03545 (MST17_03545) 726836..727078 + 243 WP_078191128.1 hypothetical protein -
MST17_RS03550 (MST17_03550) 727185..727889 + 705 WP_180027256.1 DUF1003 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-128)

Antitoxin

SpoVT-AbrB domain

(7-43)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 16163.53 Da        Isoelectric Point: 6.2194

>T239953 WP_078192327.1 NZ_CP094545:723256-723675 [Acinetobacter sp. YH16056_T]
MPTQYLLDTNICIYITKHQPEIVRQHFEKHLPDGNIFISVITLGELRFGAEKSQWKDKAFKVIDELTSIIPVIELDEHTA
VHYAQIRKQLALQGQIIGNNDLWLAAHARSNNWVMVTNNEKEFLRVDELQVENWLSKSL

Download         Length: 420 bp

>T239953 NZ_LS483415:1548497-1548832 [Streptococcus pyogenes]
TTGGACTATAAGAAATATCAGATTATCTATGCTCCTGATGTTTTAGAGAAGCTAAAAGAAATTCGTGATTATATTTCTCA
AAACTATTCCTCAACATCAGGTCAGCGTAAAATGGAGCAAATCATTAGCGACATAGAAAAACTCGAGGTTTTCCCAGAAG
TTGGTTTTGATGCCGATGAAAAATATGGTTCAAAAATCAGCCATTATCACAGCACTAAAGGTTATACCTTAAGTAAAGAT
TATATTGTCCTATACCATATCGAGGGGGAAGAAAATAGGGTCGTTATTGATTACTTGCTTCCTACTCAAAGCGACTATAT
AAAGTTATTCAAATAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8995.26 Da        Isoelectric Point: 4.6936

>AT239953 WP_078191134.1 NZ_CP094545:723026-723256 [Acinetobacter sp. YH16056_T]
MTTAKVFMTGRSQAIRLPKEFRFEGKEVEIFRRGDEVILREKPVTADQLFKVLAQMPDDFYAETRVDEPPQEREEF

Download         Length: 231 bp

>AT239953 NZ_LS483415:1548220-1548507 [Streptococcus pyogenes]
ATGACTACAGTAAAAAAAAACAGAGCTGTTACCTTTCAAGCTAATAAAGAATTGGTAAGTGAAGCAATGACAGTATTAAA
CAAAAAAAATTTAACCTTATCATCTGCTTTAAGATTATTCCTACAAAATGTCGTTGTCACAAACGAGGTTGACTTATTGA
CGGAAGAGGAGTTAGAGAAAGAAAAACTTTTCAAGCAATTTCAAGCTGAAATCAACAAAAATATTGAGGATGTTCGTCAA
GGGAAGTTTTATACCTCTGAAGAAGTGAGGGCTGAACTTGGACTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References