Detailed information of TA system TA239949

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 743813..744462
• Replicon: chromosome
• Accession: NZ_CP094541
• Organism: Acinetobacter sp. YH16040_T

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: MST16_RS03520
• Protein ID: WP_180009879.1
• Coordinates: 744043..744462 (+)
• Length: 140 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: MST16_RS03515
• Protein ID: WP_078191134.1
• Coordinates: 743813..744043 (+)
• Length: 77 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (5-128)

Antitoxin

• SpoVT-AbrB domain (7-43)

Sequences

Toxin

Protein

• Length: 140 a.a.
• Molecular weight: 16181.61 Da
• Isoelectric Point: 6.4895

>T239949 WP_180009879.1 NZ_CP094541:744043-744462 [Acinetobacter sp. YH16040_T]
MPTQYLLDTNICIYITKHQPEIVRQHFEKHLPDGNIFISVITLGELRFGAEKSQWKDKAFKVIDELTSIIPVIELDEHTA
VHYAQIRKQLALQGKMIGNNDLWLAAHARSNNWVMVTNNEKEFLRVDELQVENWLSKSL

Nucleotide

• Length: 420 bp

>T239949 NZ_LS483413:c294884-294630 [Streptococcus dysgalactiae subsp. equisimilis]
ATGTTTAATTTTACTGAAGAGGCTTGGGAAGATTACACTTCTTGGCAAAGAGAAGATAAAAAAAATCTCAAGCGTATTAA
TCGACTGATTGAAGATATCAAACGTCACCCTTTCGAAGGAATCGGAAAACCAGAACCTTTAAAATATCGGTATTCTGGTG
CCTGGTCTCGCCGTATTACAGACGAACACCGTCTCGTTTATACGGTAGAACAAAATGATATCTATTTCTTATCTTTTAGA
GATCACTATAAGTAA

Antitoxin

Protein

• Length: 77 a.a.
• Molecular weight: 8995.26 Da
• Isoelectric Point: 4.6936

>AT239949 WP_078191134.1 NZ_CP094541:743813-744043 [Acinetobacter sp. YH16040_T]
MTTAKVFMTGRSQAIRLPKEFRFEGKEVEIFRRGDEVILREKPVTADQLFKVLAQMPDDFYAETRVDEPPQEREEF

Nucleotide

• Length: 231 bp

>AT239949 NZ_LS483413:c295143-294877 [Streptococcus dysgalactiae subsp. equisimilis]
ATGGAAGCTGTTGTTTATTCAAATTTTAGAAACAATTTAAAAGATTACATGAAAAAGGTAAATGATGAATACGAGCCATT
AATGGTAGTTAATAAAAACCCTGAAGAAAATATCGTGGTCTTGTCTAAAGACAATTGGGATAGTATTCAAGAAACCATTC
GTATCATGAATAACGAATACCTCTCTGATAAAGTTCTATCAGGATTGGAACAAGTCAAACAAAAGAAAGTGACCCAACAC
CAATTATTAGAGGTGGAAGATGTTTAA