Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 7854241..7854829 Replicon chromosome
Accession NZ_CP094526
Organism Bradyrhizobium sp. ISRA464

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag MTX19_RS36410 Protein ID WP_280981501.1
Coordinates 7854476..7854829 (+) Length 118 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag MTX19_RS36405 Protein ID WP_280981500.1
Coordinates 7854241..7854495 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTX19_RS36370 (MTX19_36190) 7849270..7849500 + 231 WP_280981493.1 hypothetical protein -
MTX19_RS36375 (MTX19_36195) 7849651..7849947 + 297 WP_280981494.1 hypothetical protein -
MTX19_RS36380 (MTX19_36200) 7849937..7850509 + 573 WP_280981495.1 hypothetical protein -
MTX19_RS36385 (MTX19_36205) 7851354..7852010 + 657 WP_280981496.1 phosphoribosylanthranilate isomerase -
MTX19_RS36390 (MTX19_36210) 7852386..7852571 - 186 WP_280981497.1 hypothetical protein -
MTX19_RS36395 (MTX19_36215) 7852885..7853145 + 261 WP_280981498.1 hypothetical protein -
MTX19_RS36400 (MTX19_36220) 7853386..7853718 - 333 WP_280981499.1 hypothetical protein -
MTX19_RS36405 (MTX19_36225) 7854241..7854495 + 255 WP_280981500.1 hypothetical protein Antitoxin
MTX19_RS36410 (MTX19_36230) 7854476..7854829 + 354 WP_280981501.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
MTX19_RS36415 (MTX19_36235) 7854898..7855509 + 612 WP_280981502.1 hypothetical protein -
MTX19_RS36420 (MTX19_36240) 7855566..7857221 - 1656 WP_280985726.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(12-113)

Antitoxin

Antitoxin PemI-like

(1-84)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 12706.43 Da        Isoelectric Point: 6.0653

>T239944 WP_280981501.1 NZ_CP094526:7854476-7854829 [Bradyrhizobium sp. ISRA464]
MATKSGNYCPEAGDFVWIDLDPTIGHEQSGRRPAIVLSPHNYNAAAGLCVICPITSSVRDYPFEAKLPDGASFHGVVLAD
QPRSISWEKRPIQHAGRAPDVLLTEVRERLAALLGID

Download         Length: 354 bp

>T239944 NZ_LS483411:c183446-183168 [Haemophilus influenzae]
ATGTACGCGATTGCTTTTGATTTAGTTGTAAAAGACACTCAAGATTATCATCCAAAAGGTGTTCAGCAGGCTTATACAGA
CATTGGTGCGGTTTTAGCAAAATTTGGTTTTGTTAGAACACAAGGAAGTTTATATACCAATACAAATGAAGATATGGCAA
ACCTTTTTCAGGCAATGAATGAACTAAAACAGTTGGCGTGGATTTCTCAGTCGGTACGAGATATTCGTGCTTTTCGTATT
GAGCAATGGTCTGACTTCACTGACTTTATACGAAGTTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9390.76 Da        Isoelectric Point: 10.1998

>AT239944 WP_280981500.1 NZ_CP094526:7854241-7854495 [Bradyrhizobium sp. ISRA464]
MKVAFQKWGNSLALRVPKAFADEIGASDGKAAEMTVSDGKLVIEIARSPRRKRRYALDKLVAGITPDNRHEEVDWGRPIG
NEVW

Download         Length: 255 bp

>AT239944 NZ_LS483411:c183646-183455 [Haemophilus influenzae]
ATGGAACTAAGACAACAAATTCCAACAGGCTGTATTAAGCAATTTGGGCAATTTGGCGTGCCTTATGTGGTTGGCGAGGT
TGCGGAATTTTTGCCAGATGGCGATGCGTTGGTAAATATCACATTGTTACAATCTGGAGAAAAAGATATTTATCGCTTAT
CTCACTTACTTGAAGATCCCGAAGCTGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References