Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 8315604..8316192 Replicon chromosome
Accession NZ_CP094525
Organism Bradyrhizobium sp. ISRA463

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag MTX22_RS39060 Protein ID WP_280981501.1
Coordinates 8315839..8316192 (+) Length 118 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag MTX22_RS39055 Protein ID WP_280981500.1
Coordinates 8315604..8315858 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTX22_RS39020 (MTX22_38765) 8310635..8310865 + 231 WP_280981493.1 hypothetical protein -
MTX22_RS39025 (MTX22_38770) 8311016..8311312 + 297 WP_280981494.1 hypothetical protein -
MTX22_RS39030 (MTX22_38775) 8311302..8311874 + 573 WP_280981495.1 hypothetical protein -
MTX22_RS39035 (MTX22_38780) 8312717..8313373 + 657 WP_280981496.1 phosphoribosylanthranilate isomerase -
MTX22_RS39040 (MTX22_38785) 8313749..8313934 - 186 WP_280981497.1 hypothetical protein -
MTX22_RS39045 (MTX22_38790) 8314248..8314508 + 261 WP_280981498.1 hypothetical protein -
MTX22_RS39050 (MTX22_38795) 8314749..8315081 - 333 WP_280981499.1 hypothetical protein -
MTX22_RS39055 (MTX22_38800) 8315604..8315858 + 255 WP_280981500.1 hypothetical protein Antitoxin
MTX22_RS39060 (MTX22_38805) 8315839..8316192 + 354 WP_280981501.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
MTX22_RS39065 (MTX22_38810) 8316261..8316872 + 612 WP_280981502.1 hypothetical protein -
MTX22_RS39070 (MTX22_38815) 8317159..8318583 - 1425 WP_280981503.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(12-113)

Antitoxin

Antitoxin PemI-like

(1-84)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 12706.43 Da        Isoelectric Point: 6.0653

>T239939 WP_280981501.1 NZ_CP094525:8315839-8316192 [Bradyrhizobium sp. ISRA463]
MATKSGNYCPEAGDFVWIDLDPTIGHEQSGRRPAIVLSPHNYNAAAGLCVICPITSSVRDYPFEAKLPDGASFHGVVLAD
QPRSISWEKRPIQHAGRAPDVLLTEVRERLAALLGID

Download         Length: 354 bp

>T239939 NZ_LS483409:c1184782-1184525 [Streptococcus gallolyticus]
ATGATTAAAGCATGGTCTGACGATGCGTGGAACGACTATATGTATTGGTATAATCAAGGAAATAAAGCGACAATTAAAAA
AATTAATCGCCTAATCAAGGAGATTGACCGCACTCCTTTTACTGGCATTGGTAAACCTGAACCACTTAAACACGATTTAT
CTGGCAAATGGTCACGACGCATAACCGATGAACATCGTTTAATTTACAGTGTTGATGAAACTACTATTTACTTTTATTCT
TGCAAAGACCATTATTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9390.76 Da        Isoelectric Point: 10.1998

>AT239939 WP_280981500.1 NZ_CP094525:8315604-8315858 [Bradyrhizobium sp. ISRA463]
MKVAFQKWGNSLALRVPKAFADEIGASDGKAAEMTVSDGKLVIEIARSPRRKRRYALDKLVAGITPDNRHEEVDWGRPIG
NEVW

Download         Length: 255 bp

>AT239939 NZ_LS483409:c1185041-1184775 [Streptococcus gallolyticus]
ATGGAAGCTGTTGCATATTCAAATTTTAGACAAAATTTAAAACATTATATGAAACAAGTTAATGATGACGCTGAACCACT
TATTGTAACTTCTAAAAATATTGATGACACTGTCGTAGTCCTTTCAAAACGTGACTATGATAGCATGCAAGAAACATTTC
GCATTATGTCTAATAACTACCTAATGAATAAAATTAAACGCGGCGATGAACAATTCAAAGCAGCTAATTTTCAGACACAT
GAATTGCTCGAGGTAGATGATGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References