Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 26947..27608 Replicon plasmid unnamed
Accession NZ_CP094524
Organism Bradyrhizobium sp. ISRA443

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag MTX26_RS35075 Protein ID WP_280978507.1
Coordinates 26947..27354 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag MTX26_RS35080 Protein ID WP_280978508.1
Coordinates 27354..27608 (-) Length 85 a.a.

Genomic Context

MTX26_RS35040MTX26_RS35045MTX26_RS35050MTX26_RS35055MTX26_RS35085MTX26_RS35090MTX26_RS35095MTX26_RS35100MTX26_RS35060MTX26_RS35065MTX26_RS35070MTX26_RS35075MTX26_RS35080
Location: 23273..23890 (618 bp)
Type: Others
Protein ID: WP_280978501.1
Location: 23964..24203 (240 bp)
Type: Others
Protein ID: WP_280978502.1
Location: 24304..24579 (276 bp)
Type: Others
Protein ID: WP_280978503.1
Location: 24566..25012 (447 bp)
Type: Others
Protein ID: WP_280978504.1
Location: 27907..28848 (942 bp)
Type: Others
Protein ID: WP_280978621.1
Location: 28850..29542 (693 bp)
Type: Others
Protein ID: WP_280978509.1
Location: 29508..30374 (867 bp)
Type: Others
Protein ID: WP_280978510.1
Location: 30756..32159 (1404 bp)
Type: Others
Protein ID: WP_280978511.1
Location: 25061..25483 (423 bp)
Type: Others
Protein ID: WP_280978505.1
Location: 25483..25749 (267 bp)
Type: Others
Protein ID: WP_280978506.1
Location: 25835..26881 (1047 bp)
Type: Others
Protein ID: WP_280978620.1
Location: 26947..27354 (408 bp)
Type: Toxin
Protein ID: WP_280978507.1
Location: 27354..27608 (255 bp)
Type: Antitoxin
Protein ID: WP_280978508.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
MTX26_RS35040 (MTX26_34940)23273..23890+618WP_280978501.1hypothetical protein-
MTX26_RS35045 (MTX26_34945)23964..24203+240WP_280978502.1plasmid stabilization protein-
MTX26_RS35050 (MTX26_34950)24304..24579+276WP_280978503.1type II toxin-antitoxin system Phd/YefM family antitoxin-
MTX26_RS35055 (MTX26_34955)24566..25012+447WP_280978504.1plasmid maintenance toxin (PemK-like)-
MTX26_RS35060 (MTX26_34960)25061..25483-423WP_280978505.1type II toxin-antitoxin system VapC family toxin-
MTX26_RS35065 (MTX26_34965)25483..25749-267WP_280978506.1type II toxin-antitoxin system VapB family antitoxin-
MTX26_RS35070 (MTX26_34970)25835..26881-1047WP_280978620.1site-specific integrase-
MTX26_RS35075 (MTX26_34975)26947..27354-408WP_280978507.1type II toxin-antitoxin system VapC family toxinToxin
MTX26_RS35080 (MTX26_34980)27354..27608-255WP_280978508.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
MTX26_RS35085 (MTX26_34985)27907..28848+942WP_280978621.1DUF1403 family protein-
MTX26_RS35090 (MTX26_34990)28850..29542+693WP_280978509.1SMC-Scp complex subunit ScpB-
MTX26_RS35095 (MTX26_34995)29508..30374+867WP_280978510.1hypothetical protein-
MTX26_RS35100 (MTX26_35000)30756..32159+1404WP_280978511.1toll/interleukin-1 receptor domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideConjugative plasmid--1..316663316663


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-116)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-69)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 14757.74 Da        Isoelectric Point: 6.3309

>T239934 WP_280978507.1 NZ_CP094524:c27354-26947 [Bradyrhizobium sp. ISRA443]
MYLVDTNVVSEARRGSAQATGWLRSVDPASVHLSTLTLGEIMRGIALKQKSDPKAAAHLAEWLRKLRHDHADRILAVTDQ
ISVEWGRIAAIRPRGDIDGQIAATAIVHDLILVTRNVGDFEDTGATVINPWEESA

Download         Length: 408 bp

>T239934 NZ_LS483408:1268096-1268941 [Streptococcus uberis]
ATGAATAAAGCTAAGCTAACAGCACTCTGTCATAAAATATCAAAGAATACTGGATTAACCTTTAATTCCGTGATGACCTA
TTACTTTCTTGAAGTGATTTTGAAAAAATTAAGTCAGAGTACCTACTCAAATCACTATATCTTCAAAGGAGGATTCCTAC
TATCAAATGTTATCGGAGTTGAATCTCGTAGCACTGTTGATATTGATTTTTTGTTCCATCAAATGACACTCTCAGAAGAT
ACTGTGAAGCAGCAACTCAAGGAAATTTTAGCAGATTCCGAAGAAGGTATATCTTTTGTGATTCAATCAACCACAGCTAT
AAAAGAAAGTGATGACTATGGTGGCTATCGTGCAACCATTTTATGCCAACTTGAGAATATTAAACAAATTATCCATTTGG
ATATTGCAACTGGGGATATTGTAACTCCACAGCCTATTACATATGATTACAAAGCTATTTTTAATGAAGACACCTTTCCA
ATCATTGCTTATACAATTGAAACAATTCTAGCTGAAAAACTCCAAACCATCTATTCACGCAACTTCTTGAACAGCAGAAG
CAAAGATTTTTACGATGTTTATATTCTTTCAAAACTGAAGAAAGAAGACATTGACTTCATTCAATTGAAAAATGCCTGTC
AGAGAACATTTTCATATCGCGAAACAGAACTCGATTTTGTAAAGATTATTGAACTACTCGAGAGGTTCAAATCTGACCCT
ATTCAGAATAAACAATGGCAAAATTATTCAAAAAAATATAGCTATACTAAGGGGATTTCACTTGCAGATGTTCTTGATGA
GATGATTCGTCTCATAACAGTTCTCATTTCTATAAATTCTGATTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9187.29 Da        Isoelectric Point: 4.7420

>AT239934 WP_280978508.1 NZ_CP094524:c27608-27354 [Bradyrhizobium sp. ISRA443]
MEWSLQDAKNQFSKVVQKARLEGPQVVTLRGERAAVVLSAADYDALRSGRPTLVDDLLAGPGWDDEMAEAVTRRANTPSR
DAAF

Download         Length: 255 bp

>AT239934 NZ_LS483408:1267509-1268099 [Streptococcus uberis]
ATGTCAAAAAAAGAGATTCTACTCGATTTTATAGAAAAGAACAATGGCATTATCACAAACAAAGATTGTAAAGCACTAGG
TATTCCAACAATATATCTGACAAGACTAGAGAAAGAAGGCATTATCTTCCGAGTTGAAAAAGGTATTTTCCTAACCCAAA
ACGGAGACTATGATGAATACTACTTCTTTCAATATCGTTTTCCTAAGGCTATTTTCTCTTATATTTCGGCACTGTATCTA
CAACAGTTTACGGATGAAATTCCACAATATTTTGATGTGACAGTTCCTAGAGGCTACCGCTTTAATACTCCTCCAGCAAA
TCTGAACATTCATTCCGTTTCTAAGGAATATAGCGAACTAGGAATTACACTTGTAAAAACACCTATGGGAAACAAGGTAA
GAGTGTATGATTTAGAACGCATTATCTGTGATTTTGTGATTCATCGAGAAAAAATAGATACTGAGCTTTTTGTCAAAACA
CTTCAACATTATGGAAACTATTCTAAAAAAAATCTTACAAAACTCTATGAATATGCGACAAAAATGAACACCTTGGACAA
GGTCAAACAAACTCTGGAGGTCCTAGTATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References