Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 4296410..4297031 Replicon chromosome
Accession NZ_CP094521
Organism Bradyrhizobium sp. ISRA437

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag MTX18_RS20415 Protein ID WP_280972003.1
Coordinates 4296630..4297031 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag MTX18_RS20410 Protein ID WP_280972002.1
Coordinates 4296410..4296640 (+) Length 77 a.a.

Genomic Context

MTX18_RS20395MTX18_RS20400MTX18_RS20410MTX18_RS20415MTX18_RS20420MTX18_RS20430MTX18_RS20385MTX18_RS20390MTX18_RS20405MTX18_RS20425MTX18_RS20435MTX18_RS20440
Location: 4293047..4294267 (1221 bp)
Type: Others
Protein ID: WP_280971999.1
Location: 4294301..4294945 (645 bp)
Type: Others
Protein ID: WP_280972000.1
Location: 4296410..4296640 (231 bp)
Type: Antitoxin
Protein ID: WP_280972002.1
Location: 4296630..4297031 (402 bp)
Type: Toxin
Protein ID: WP_280972003.1
Location: 4297039..4297245 (207 bp)
Type: Others
Protein ID: WP_280990690.1
Location: 4298921..4299859 (939 bp)
Type: Others
Protein ID: WP_280972005.1
Location: 4291910..4292152 (243 bp)
Type: Others
Protein ID: WP_280971997.1
Location: 4292173..4292952 (780 bp)
Type: Others
Protein ID: WP_280971998.1
Location: 4294998..4296212 (1215 bp)
Type: Others
Protein ID: WP_280972001.1
Location: 4297199..4298716 (1518 bp)
Type: Others
Protein ID: WP_280972004.1
Location: 4299886..4300563 (678 bp)
Type: Others
Protein ID: WP_280972006.1
Location: 4300470..4300796 (327 bp)
Type: Others
Protein ID: WP_280972007.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
MTX18_RS20385 (MTX18_20320)4291910..4292152-243WP_280971997.1hypothetical protein-
MTX18_RS20390 (MTX18_20325)4292173..4292952-780WP_280971998.1DUF899 domain-containing protein-
MTX18_RS20395 (MTX18_20330)4293047..4294267+1221WP_280971999.1helix-turn-helix domain-containing protein-
MTX18_RS20400 (MTX18_20335)4294301..4294945+645WP_280972000.1glutamine cyclotransferase-
MTX18_RS20405 (MTX18_20340)4294998..4296212-1215WP_280972001.1MFS transporter-
MTX18_RS20410 (MTX18_20345)4296410..4296640+231WP_280972002.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
MTX18_RS20415 (MTX18_20350)4296630..4297031+402WP_280972003.1PIN domain-containing proteinToxin
MTX18_RS204204297039..4297245+207WP_280990690.1AAA family ATPase-
MTX18_RS20425 (MTX18_20360)4297199..4298716-1518WP_280972004.1MFS transporter-
MTX18_RS20430 (MTX18_20365)4298921..4299859+939WP_280972005.1LysR family transcriptional regulator-
MTX18_RS20435 (MTX18_20370)4299886..4300563-678WP_280972006.1LysR substrate-binding domain-containing protein-
MTX18_RS20440 (MTX18_20375)4300470..4300796-327WP_280972007.1LysR family transcriptional regulator-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-119)

Antitoxin

SpoVT-AbrB domain

(5-37)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14887.11 Da        Isoelectric Point: 5.6254

>T239930 WP_280972003.1 NZ_CP094521:4296630-4297031 [Bradyrhizobium sp. ISRA437]
MPGDFFDTNVLVHLASGDPLKADRAEAVISRGGVISVQVLNEIANVARRKMRMSWTETRAFLTILRNLLTIYPLTQEIHD
AGLDLAERYGLSMFDAMIAASALQAGCDRLWSEDMQHNQVLDNSLRIVNPFRV

Download         Length: 402 bp

>T239930 NZ_LS483406:263589-263891 [Stenotrophomonas maltophilia]
ATGGCTATCAAGAAGAAAGTTGAACTCGAAGCATTTGATGTGGCCGAACACCTTCATACACCGAAGGAAATGGCGGCCTA
TCTCGATGCATGCATCGAAGAAAGCGACGGCGATTCGGCATTCATCGCCAAGGCGCTGGGCGATATCGCGCGTGCCCAAG
GGATGAGCAAGGTCGCACGTGCGGCGGGCCTGTCGCGGGAGAGTCTGTATCGTGCCCTGTCTGGCGAGCGCAGCCCTGAT
TTCTCGACCATCCTGAAGGTGACTCGTGCCCTGGGTGTGCGCCTGCATGCCAGCGCTGCATGA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8600.81 Da        Isoelectric Point: 7.0171

>AT239930 WP_280972002.1 NZ_CP094521:4296410-4296640 [Bradyrhizobium sp. ISRA437]
MQVAKWGNSLAIRLPAAVVEALELKEGDEIEIHVADERNFGVARKPGREELLARLRAFRGRLPADFKFDRDEANAR

Download         Length: 231 bp

>AT239930 NZ_LS483406:263243-263548 [Stenotrophomonas maltophilia]
ATGAAGATCCAGCGTACCCGTCAGTTCGCGACATGGATTGACGCTCTCAAGGACGTAACCGCACGCGCTCGCATCCTGGC
CCGTATCGGTCGGCTCGCTGAAGGCCATCCTGGTGATCACCGCTATCTGGCGGATGGCGTTTCTGAATTGCGTATCGATG
CAGGACCCGGTTACCGCGTGTACTACACCCAGCGGGGCAGGCAGTTGGTGATTCTTCTGGTCGGAGGCGACAAGGGTTCG
CAACAGCGCGATATAGAGAAGGCCAAGGAGATTGCGCGTGCCCTGCGAGCATCGAACTGGTTGTAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References