Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2294872..2295545 Replicon chromosome
Accession NZ_CP094515
Organism Bradyrhizobium sp. ISRA426

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag MTX24_RS10525 Protein ID WP_280969128.1
Coordinates 2295123..2295545 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag MTX24_RS10520 Protein ID WP_280969127.1
Coordinates 2294872..2295126 (+) Length 85 a.a.

Genomic Context


MTX24_RS10505MTX24_RS10510MTX24_RS10515MTX24_RS10520MTX24_RS10525MTX24_RS10530MTX24_RS10535
Location: 2291569..2292258 (690 bp)
Type: Others
Protein ID: WP_280970898.1
Location: 2293754..2294080 (327 bp)
Type: Others
Protein ID: WP_280969126.1
Location: 2294171..2294800 (630 bp)
Type: Others
Protein ID: Protein_2079
Location: 2294872..2295126 (255 bp)
Type: Antitoxin
Protein ID: WP_280969127.1
Location: 2295123..2295545 (423 bp)
Type: Toxin
Protein ID: WP_280969128.1
Location: 2295821..2296141 (321 bp)
Type: Others
Protein ID: Protein_2082
Location: 2297032..2298576 (1545 bp)
Type: Others
Protein ID: WP_280969129.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
MTX24_RS10505 (MTX24_10460)2291569..2292258+690WP_280970898.1YopT-type cysteine protease domain-containing protein-
MTX24_RS10510 (MTX24_10465)2293754..2294080+327WP_280969126.1IS66 family insertion sequence element accessory protein TnpB-
MTX24_RS10515 (MTX24_10470)2294171..2294800+630Protein_2079IS66 family transposase zinc-finger binding domain-containing protein-
MTX24_RS10520 (MTX24_10475)2294872..2295126+255WP_280969127.1plasmid stabilization proteinAntitoxin
MTX24_RS10525 (MTX24_10480)2295123..2295545+423WP_280969128.1type II toxin-antitoxin system VapC family toxinToxin
MTX24_RS10530 (MTX24_10485)2295821..2296141-321Protein_2082transposase-
MTX24_RS10535 (MTX24_10490)2297032..2298576-1545WP_280969129.1acyl-CoA dehydrogenase family protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--2275383..229864823265
-flankIS/Tn--2293754..2294080326


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-125)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 141 a.a.        Molecular weight: 14900.11 Da        Isoelectric Point: 5.7030

>T239923 WP_280969128.1 NZ_CP094515:2295123-2295545 [Bradyrhizobium sp. ISRA426]
MILLDTNVVSEAMKPDPHPTVRDWLDAQAAETLFLSSVTIAELLFGIGALPRGKRKDRLAAALDGVLDLFATRILPFDTD
AARRYAELAVKARTAGKGFPTPDGYIAAIAAAHGFAVASRDTSAFNAVGLTMIDPWTVTS

Download         Length: 423 bp

>T239923 NZ_LS483396:c309291-309037 [Micrococcus luteus NCTC 2665]
ATGCGCCTCGTGTCGGACCGCTCCGCCTGGGATGACTGCACGCACTGGCAGACCACGGACCGCAAGGTCCTCCAACGGAT
CAACACCCTCATCGACGCCGCCCTGCGTGATCCCCTCGACGGGATCGGCAAACCCGAGCAGCTGAAGTACGGCGCGGCCG
GGGCATGGTCCCGACGCATCACGGAGGAGCACAGGCTCGTCTACCTCGTCGACGGCGAGGACCTGATCATCCTCCAGGCG
AGGTATCACTACTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9265.54 Da        Isoelectric Point: 7.2070

>AT239923 WP_280969127.1 NZ_CP094515:2294872-2295126 [Bradyrhizobium sp. ISRA426]
MAAVTIRNLSEEAHRALKVRAAQHNRSAEAEMRAILEAAVRPEGRLQLGTALSEMSRKIGLTNADVEALEQGRDARPAEP
MRFE

Download         Length: 255 bp

>AT239923 NZ_LS483396:c309495-309292 [Micrococcus luteus NCTC 2665]
GTGCCTCCCGAGTTCGACCTCGCCGACTGGTACATAAGCAGGCACCACATCGCGCCGGAGGAGGCCCCCATGTCCATCAG
TGCCAGTGAAGCCCGCAAGACCCTGTTCCCGCTCATCGAGCGAGTGACTGCGGACCGCGACGCCGTCGAGATCGTCTCCC
GCAAGGGCAACGCCGTTCTCATGCCCGCGGACGGGGACGCCTGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References