Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1839699..1839844 Replicon chromosome
Accession NZ_CP094512
Organism Klebsiella pneumoniae strain SHX180

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1839735..1839837 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1839699..1839844 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTX44_RS08915 (MTX44_08905) 1834829..1836889 + 2061 WP_004151449.1 oligopeptidase B -
MTX44_RS08920 (MTX44_08910) 1836893..1837552 - 660 WP_002911407.1 exodeoxyribonuclease X -
MTX44_RS08925 (MTX44_08915) 1837631..1837861 - 231 WP_002911406.1 DNA polymerase III subunit theta -
MTX44_RS08930 (MTX44_08920) 1837974..1838348 + 375 WP_004151448.1 CopC domain-containing protein YobA -
MTX44_RS08935 (MTX44_08925) 1838352..1839221 + 870 WP_257695451.1 copper homeostasis membrane protein CopD -
MTX44_RS08940 (MTX44_08930) 1839238..1839576 + 339 WP_002911404.1 YebY family protein -
- 1839699..1839844 - 146 - - Antitoxin
- 1839735..1839837 + 103 - - Toxin
MTX44_RS08945 (MTX44_08935) 1840213..1840356 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
MTX44_RS08950 (MTX44_08940) 1840461..1841429 - 969 WP_004151446.1 VirK/YbjX family protein -
MTX44_RS08955 (MTX44_08945) 1841586..1842239 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
MTX44_RS08960 (MTX44_08950) 1842236..1842427 - 192 WP_002911395.1 YebW family protein -
MTX44_RS08965 (MTX44_08955) 1842525..1842764 - 240 WP_002911393.1 YebV family protein -
MTX44_RS08970 (MTX44_08960) 1842880..1844313 - 1434 WP_021440382.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T239909 NZ_CP094512:1839735-1839837 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT239909 NZ_CP094512:c1839844-1839699 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References