Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 168567..169126 Replicon chromosome
Accession NZ_CP094467
Organism Faecalibacterium sp. I4-1-79

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MTP36_RS00820 Protein ID WP_118658513.1
Coordinates 168836..169126 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MTP36_RS00815 Protein ID WP_112091363.1
Coordinates 168567..168839 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTP36_RS00790 (MTP36_00790) 163968..164777 + 810 WP_006735344.1 gluconate 5-dehydrogenase -
MTP36_RS00795 (MTP36_00795) 164875..165219 + 345 WP_249252810.1 cupin domain-containing protein -
MTP36_RS00800 (MTP36_00800) 165263..165898 + 636 WP_015537141.1 RpiB/LacA/LacB family sugar-phosphate isomerase -
MTP36_RS00805 (MTP36_00805) 165914..166330 + 417 WP_015537140.1 DUF1622 domain-containing protein -
MTP36_RS00810 (MTP36_00810) 166568..168307 + 1740 WP_117554668.1 ammonium transporter -
MTP36_RS00815 (MTP36_00815) 168567..168839 + 273 WP_112091363.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
MTP36_RS00820 (MTP36_00820) 168836..169126 + 291 WP_118658513.1 type II toxin-antitoxin system YafQ family toxin Toxin
MTP36_RS00825 (MTP36_00825) 169203..170987 - 1785 WP_249252812.1 threonine--tRNA ligase -
MTP36_RS00830 (MTP36_00830) 171070..171255 - 186 WP_143406238.1 hypothetical protein -
MTP36_RS00835 (MTP36_00835) 171470..172390 + 921 WP_097779343.1 nucleotidyltransferase -
MTP36_RS00840 (MTP36_00840) 172474..172929 - 456 WP_249252814.1 MarR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(7-95)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-88)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11123.96 Da        Isoelectric Point: 9.1748

>T239875 WP_118658513.1 NZ_CP094467:168836-169126 [Faecalibacterium sp. I4-1-79]
MRETKLTIIPTTQFRKDYKLARKRGLKIELLQDVIACLAMGEPLPEKNRDHALTGDWVGHRECHIQPDWLLVYRVQNDVL
VLTLTRTGTHSDLFGK

Download         Length: 291 bp

>T239875 NZ_LS483374:c1113105-1112851 [Streptococcus pneumoniae]
TTGTATAAATTAGTTCCAACAAGACGTTTCATCAAGCAATTGAAAAAATTGGACCGTTATACGCAGAAGCTAATTACAAA
CTATTTACAAACCAATGTTTTGGAAGACCCAAGACGACACGGAAAGGCTTTGGTTGGTAATCGCGTTGGTCAATGGCGCT
ATAGAATTGGTAATTATCGAGTTATCGTACAAATTGTAGATGATGAATTAGTCGTTGCTACTCTAGAAGTTGGTCATCGG
AGAGATATTTATTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10071.49 Da        Isoelectric Point: 4.6677

>AT239875 WP_112091363.1 NZ_CP094467:168567-168839 [Faecalibacterium sp. I4-1-79]
MATTNVSIRMDADLKAQADALFAELGMNLSTAFNIFVRQSLREGGIPFEIRTERPNKETVAAMLEAEHIAADPKAKKYRD
LDELFADLEK

Download         Length: 273 bp

>AT239875 NZ_LS483374:c1113349-1113107 [Streptococcus pneumoniae]
ATGACTACTATTACATTAAAAGTTTCTGAAGCTGATAAAACATTTATGAAAGCAATGGCTAAGTTTGAAGGAGTTTCCCT
TTCGGAACTTATTCGCACCAAAACTCTTGAAGCCCTAGAAGATGAATACGATGCTCGTGTGGCAGATTTAGCCTATCAAG
AGTATTTAGAAGACTTGGAAAAAGGAGTTGAACCCATTACTTGGGAAGAAATGATGCATGATTTAGGCTTGAAGGATGAA
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References