Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2058269..2058414 Replicon chromosome
Accession NZ_CP094451
Organism Klebsiella pneumoniae subsp. rhinoscleromatis strain KP4831

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2058305..2058407 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2058269..2058414 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MRR30_RS10015 (MRR30_10015) 2053399..2055459 + 2061 WP_004151449.1 oligopeptidase B -
MRR30_RS10020 (MRR30_10020) 2055463..2056122 - 660 WP_002911407.1 exodeoxyribonuclease X -
MRR30_RS10025 (MRR30_10025) 2056201..2056431 - 231 WP_002911406.1 DNA polymerase III subunit theta -
MRR30_RS10030 (MRR30_10030) 2056544..2056918 + 375 WP_004151448.1 CopC domain-containing protein YobA -
MRR30_RS10035 (MRR30_10035) 2056922..2057791 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
MRR30_RS10040 (MRR30_10040) 2057808..2058146 + 339 WP_002911404.1 YebY family protein -
- 2058269..2058414 - 146 - - Antitoxin
- 2058305..2058407 + 103 - - Toxin
MRR30_RS10045 (MRR30_10045) 2058782..2058925 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
MRR30_RS10050 (MRR30_10050) 2059030..2059998 - 969 WP_004151446.1 VirK/YbjX family protein -
MRR30_RS10055 (MRR30_10055) 2060155..2060808 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
MRR30_RS10060 (MRR30_10060) 2060805..2060996 - 192 WP_002911395.1 YebW family protein -
MRR30_RS10065 (MRR30_10065) 2061094..2061333 - 240 WP_002911393.1 YebV family protein -
MRR30_RS10070 (MRR30_10070) 2061449..2062882 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T239835 NZ_CP094451:2058305-2058407 [Klebsiella pneumoniae subsp. rhinoscleromatis]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT239835 NZ_CP094451:c2058414-2058269 [Klebsiella pneumoniae subsp. rhinoscleromatis]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References