23983

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 1004086..1005806 Replicon chromosome
Accession NC_012917
Organism Pectobacterium carotovorum subsp. carotovorum PC1

Toxin (Protein)


Gene name pmenT Uniprot ID C6DAA6
Locus tag PC1_RS04310 Protein ID WP_012773555.1
Coordinates 1005150..1005806 (-) Length 219 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID C6DAA5
Locus tag PC1_RS04305 Protein ID WP_012773554.1
Coordinates 1004086..1005153 (-) Length 356 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PC1_RS04295 1000254..1000970 - 717 WP_012773552.1 M48 family metallopeptidase -
PC1_RS04300 1000970..1004065 - 3096 WP_012773553.1 HsdR family type I site-specific deoxyribonuclease -
PC1_RS04305 1004086..1005153 - 1068 WP_012773554.1 macro domain-containing protein Antitoxin
PC1_RS04310 1005150..1005806 - 657 WP_012773555.1 DUF4433 domain-containing protein Toxin
PC1_RS04315 1005819..1007060 - 1242 WP_012773556.1 restriction endonuclease subunit S -
PC1_RS04320 1007060..1009504 - 2445 WP_012773557.1 type I restriction-modification system subunit M -
PC1_RS04325 1009545..1009784 - 240 WP_012773558.1 hypothetical protein -
PC1_RS22465 1009861..1010292 + 432 WP_196219332.1 ash family protein -
PC1_RS04330 1010184..1010645 + 462 WP_012773559.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 983642..1013205 29563


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(17-217)

Antitoxin

Macro domain

(18-129)


Sequences

Toxin        


Download         Length: 219 a.a.        Molecular weight: 24878.23 Da        Isoelectric Point: 7.4755

>T23983 WP_012773555.1 NC_012917:c1005806-1005150 [Pectobacterium carotovorum subsp. carotovorum PC1]
MANDYSASLNPQKALIWRIVHRDNIPWILDNGLHCGNSPVQAGNWINIGNPELIGKRAGHPVPAGAGGTLHDYVPFYFTP
FSPMLMNIHSGRGGIKQRPNEEIVILVSSLRTVAAQNVPFVFTDSHAYYNWANYYTDLNNLNQIDWPILQARDFRRDPDD
PGKFERYQAEALIWRHCPITLLSGMVCYNDSVKLQLEQWLSQRNLTMPVHARAGWYFS

Download         Length: 657 bp

>T23983 NC_012917:c1005806-1005150 [Pectobacterium carotovorum subsp. carotovorum PC1]
ATGGCTAATGACTACAGCGCCAGTCTCAACCCACAAAAAGCCCTGATCTGGCGTATTGTCCATCGGGATAATATCCCGTG
GATACTGGACAACGGCCTGCACTGCGGCAACAGCCCGGTACAGGCGGGAAACTGGATCAATATCGGCAACCCGGAGCTTA
TCGGCAAACGCGCCGGGCATCCGGTGCCTGCCGGGGCGGGTGGTACGTTGCATGACTATGTGCCATTTTACTTTACTCCC
TTCTCGCCAATGCTGATGAATATCCACAGCGGGCGCGGCGGTATTAAGCAACGCCCCAATGAAGAAATCGTCATTCTGGT
CAGCAGTCTGCGCACCGTGGCAGCGCAAAATGTTCCTTTTGTGTTTACCGATAGCCACGCCTACTATAACTGGGCTAACT
ATTACACCGATTTGAACAATCTGAACCAAATTGACTGGCCTATTTTACAGGCGCGGGATTTCCGCCGCGATCCTGACGAT
CCGGGCAAATTTGAACGCTATCAGGCCGAAGCGCTGATCTGGCGACACTGCCCAATCACACTGCTGAGCGGGATGGTTTG
TTACAACGACAGCGTCAAGTTACAATTAGAACAGTGGCTGTCGCAACGCAATCTGACAATGCCCGTTCACGCACGGGCCG
GGTGGTACTTCTCATGA

Antitoxin


Download         Length: 356 a.a.        Molecular weight: 40554.95 Da        Isoelectric Point: 7.0449

>AT23983 WP_012773554.1 NC_012917:c1005153-1004086 [Pectobacterium carotovorum subsp. carotovorum PC1]
MITFTQGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPANMKAYALACKQKQVMTGKMFITETGELMGPRWIVNFPTK
QHWRADSRMAWIEDGLQDLRRFLIEKQVQSIAIPPLGAGNGGLNWPDVRAHIESALGDLQDINILIYEPTEKYLNVAKST
GVKKLTPARAMIAELVRRYWVLGIECSLLEIQKLAWLLQRAIELHRQDDVLKLRFDAHYYGPYAPNLSHLLNALDGTYLK
AEKRIPDSQPLDVIWFNDREKDRIEAYLNSEAKEWLPALKQVSQLIDGFESPFGMELLATVDWLLARGECQPTLDSVKEG
LSQWPAGERWASRKMKLFDDNNLQFAINRVMEFHR

Download         Length: 1068 bp

>AT23983 NC_012917:c1005153-1004086 [Pectobacterium carotovorum subsp. carotovorum PC1]
ATGATCACATTTACACAAGGCAACTTACTGGATGCGCCCGTGGAAGCACTGGTGAATACGGTTAATACCGTCGGTGTCAT
GGGTAAGGGTATCGCGCTGATGTTCAAAGAACGCTTTCCCGCCAATATGAAAGCCTACGCCCTCGCCTGCAAACAGAAGC
AGGTGATGACCGGCAAAATGTTTATTACCGAAACCGGCGAACTGATGGGGCCGCGCTGGATTGTCAACTTCCCTACCAAA
CAGCACTGGCGAGCCGACTCGCGTATGGCGTGGATCGAAGACGGTTTGCAGGACTTACGCCGCTTTTTGATCGAGAAACA
GGTGCAGTCCATCGCCATTCCGCCACTGGGCGCGGGCAACGGTGGCCTCAACTGGCCGGACGTCCGGGCGCATATTGAAT
CTGCGCTAGGCGATCTTCAGGACATTAATATCCTGATTTATGAGCCCACCGAAAAATACCTGAACGTCGCCAAAAGCACC
GGCGTAAAAAAGCTCACCCCTGCCAGAGCGATGATCGCTGAACTGGTGCGCCGCTACTGGGTGCTGGGAATAGAATGCAG
CCTGCTGGAAATCCAGAAACTGGCATGGCTTTTACAACGCGCGATTGAACTGCACCGGCAGGACGATGTGCTAAAACTGC
GGTTCGATGCTCACTATTACGGCCCCTACGCACCGAACCTGAGTCATCTGCTTAATGCGCTGGACGGCACCTATCTGAAA
GCCGAGAAACGAATTCCAGACAGTCAGCCGCTGGACGTGATCTGGTTTAACGATCGGGAGAAAGATCGCATCGAAGCCTA
TTTGAATAGTGAAGCCAAAGAGTGGCTCCCCGCGCTGAAACAAGTCAGTCAGCTAATTGACGGCTTTGAATCTCCATTCG
GTATGGAACTACTGGCGACCGTAGACTGGCTGTTGGCCCGGGGGGAATGCCAGCCCACGCTGGATTCCGTTAAAGAAGGG
CTGAGCCAGTGGCCTGCGGGTGAACGCTGGGCCAGCCGCAAGATGAAGTTATTCGATGATAATAATCTGCAATTCGCCAT
TAACCGCGTAATGGAGTTCCATCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB C6DAA6

Antitoxin

Source ID Structure
AlphaFold DB C6DAA5

References