Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/Cpta(toxin) |
Location | 742385..743045 | Replicon | chromosome |
Accession | NC_012917 | ||
Organism | Pectobacterium carotovorum subsp. carotovorum PC1 |
Toxin (Protein)
Gene name | cptA | Uniprot ID | A0A7W2E4X8 |
Locus tag | PC1_RS03205 | Protein ID | WP_012773341.1 |
Coordinates | 742632..743045 (+) | Length | 138 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | C6D8Y5 |
Locus tag | PC1_RS03200 | Protein ID | WP_012773340.1 |
Coordinates | 742385..742651 (+) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PC1_RS03180 | 738377..739381 | - | 1005 | WP_012773336.1 | LacI family DNA-binding transcriptional regulator | - |
PC1_RS03185 | 739425..740033 | - | 609 | WP_012773337.1 | HD domain-containing protein | - |
PC1_RS03190 | 740446..741093 | + | 648 | WP_012773338.1 | hemolysin III family protein | - |
PC1_RS03195 | 741148..742149 | - | 1002 | WP_012773339.1 | tRNA-modifying protein YgfZ | - |
PC1_RS03200 | 742385..742651 | + | 267 | WP_012773340.1 | FAD assembly factor SdhE | Antitoxin |
PC1_RS03205 | 742632..743045 | + | 414 | WP_012773341.1 | protein YgfX | Toxin |
PC1_RS03210 | 743115..744050 | + | 936 | WP_012773342.1 | 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF | - |
PC1_RS03215 | 744095..744418 | - | 324 | WP_012773343.1 | hypothetical protein | - |
PC1_RS03220 | 744447..744965 | - | 519 | WP_012773344.1 | flavodoxin FldB | - |
PC1_RS03225 | 745296..745682 | - | 387 | WP_012773345.1 | thioesterase family protein | - |
PC1_RS03230 | 745883..747211 | - | 1329 | WP_012773346.1 | MHS family MFS transporter | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 138 a.a. Molecular weight: 16302.21 Da Isoelectric Point: 10.6525
>T23980 WP_012773341.1 NC_012917:742632-743045 [Pectobacterium carotovorum subsp. carotovorum PC1]
VAQWQCDLRVSWRMQLLSLIVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQ
EWQIVKRPWLLKNGVLLSLQAVNGKDRQQLWLASDSMGDDEWRHLRQLLLQQKNWAR
VAQWQCDLRVSWRMQLLSLIVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQ
EWQIVKRPWLLKNGVLLSLQAVNGKDRQQLWLASDSMGDDEWRHLRQLLLQQKNWAR
Download Length: 414 bp
>T23980 NC_012917:742632-743045 [Pectobacterium carotovorum subsp. carotovorum PC1]
GTGGCCCAGTGGCAATGTGATCTTCGCGTTTCCTGGCGTATGCAACTGCTTTCATTGATTGTGCATGGCCTATTAGTATT
GCTCATTCTTCTGGCACCGTGGCCGGACGGCTATGCATGGCTGTGGCTATGCCTGGTCACGATGGTGATGTTCGGTTTTA
TCCGTAGCCAAAGGAATATCAAATCCCGGCAGGGGGAAATCGTTTTGCTCAGCGAAACGACCCTGAACTGGCGGCAGCAG
GAATGGCAGATCGTTAAACGACCGTGGTTGCTGAAAAATGGCGTATTGCTGTCATTGCAGGCAGTGAACGGTAAAGACAG
ACAACAACTGTGGCTGGCATCGGACAGCATGGGCGATGACGAATGGCGTCATCTGCGTCAGCTTCTTTTGCAGCAGAAAA
ACTGGGCGAGATAG
GTGGCCCAGTGGCAATGTGATCTTCGCGTTTCCTGGCGTATGCAACTGCTTTCATTGATTGTGCATGGCCTATTAGTATT
GCTCATTCTTCTGGCACCGTGGCCGGACGGCTATGCATGGCTGTGGCTATGCCTGGTCACGATGGTGATGTTCGGTTTTA
TCCGTAGCCAAAGGAATATCAAATCCCGGCAGGGGGAAATCGTTTTGCTCAGCGAAACGACCCTGAACTGGCGGCAGCAG
GAATGGCAGATCGTTAAACGACCGTGGTTGCTGAAAAATGGCGTATTGCTGTCATTGCAGGCAGTGAACGGTAAAGACAG
ACAACAACTGTGGCTGGCATCGGACAGCATGGGCGATGACGAATGGCGTCATCTGCGTCAGCTTCTTTTGCAGCAGAAAA
ACTGGGCGAGATAG
Antitoxin
Download Length: 89 a.a. Molecular weight: 10465.94 Da Isoelectric Point: 6.2223
>AT23980 WP_012773340.1 NC_012917:742385-742651 [Pectobacterium carotovorum subsp. carotovorum PC1]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLSDSDKRTFVRLLQSDDPDLFNWLMNHGEPKDGELKRMISLIQTRN
KDRGPVAM
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLSDSDKRTFVRLLQSDDPDLFNWLMNHGEPKDGELKRMISLIQTRN
KDRGPVAM
Download Length: 267 bp
>AT23980 NC_012917:742385-742651 [Pectobacterium carotovorum subsp. carotovorum PC1]
ATGGAAATCGATAATAAATCACGCATTCATTGGGCATGCCGCCGGGGTATGCGTGAGTTGGATATCGCGATCATGCCGTT
TTTTGAGCATGACTACGACACACTCAGTGACAGCGATAAGCGCACCTTTGTGCGCCTGTTACAAAGCGATGATCCCGATT
TATTCAACTGGCTGATGAACCACGGCGAGCCGAAAGACGGAGAGCTGAAACGCATGATTTCTCTTATTCAAACGCGAAAT
AAAGATCGTGGCCCAGTGGCAATGTGA
ATGGAAATCGATAATAAATCACGCATTCATTGGGCATGCCGCCGGGGTATGCGTGAGTTGGATATCGCGATCATGCCGTT
TTTTGAGCATGACTACGACACACTCAGTGACAGCGATAAGCGCACCTTTGTGCGCCTGTTACAAAGCGATGATCCCGATT
TATTCAACTGGCTGATGAACCACGGCGAGCCGAAAGACGGAGAGCTGAAACGCATGATTTCTCTTATTCAAACGCGAAAT
AAAGATCGTGGCCCAGTGGCAATGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7W2E4X8 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7W2E501 |