Detailed information of TA system TA239781

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT(toxin)
• Location: 6846..7329
• Replicon: plasmid unnamed
• Accession: NZ_CP094360
• Organism: Acidithiobacillus sp. YTS05

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: MQE22_RS13715
• Protein ID: WP_255790356.1
• Coordinates: 7057..7329 (-)
• Length: 91 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: MQE22_RS13710
• Protein ID: WP_255790354.1
• Coordinates: 6846..7076 (-)
• Length: 77 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MQE22_RS13690 (MQE22_13685)	2232..4031	+	1800	WP_255790346.1	plasmid recombination protein	-
MQE22_RS13695 (MQE22_13690)	4436..5728	-	1293	WP_255790348.1	replication protein	-
MQE22_RS13700 (MQE22_13695)	5979..6326	-	348	WP_255790350.1	type II toxin-antitoxin system RelE/ParE family toxin	-
MQE22_RS13705 (MQE22_13700)	6256..6498	-	243	WP_255790352.1	ribbon-helix-helix protein, CopG family	-
MQE22_RS13710 (MQE22_13705)	6846..7076	-	231	WP_255790354.1	ribbon-helix-helix protein, CopG family	Antitoxin
MQE22_RS13715 (MQE22_13710)	7057..7329	-	273	WP_255790356.1	BrnT family toxin	Toxin
MQE22_RS13720 (MQE22_13715)	7365..7769	-	405	WP_255790332.1	hypothetical protein	-
MQE22_RS13725 (MQE22_13720)	7827..8453	-	627	WP_255790335.1	recombinase family protein	-
MQE22_RS13730 (MQE22_13725)	8510..8770	+	261	WP_255790337.1	DUF4160 domain-containing protein	-
MQE22_RS13735 (MQE22_13730)	8851..9054	+	204	WP_255790338.1	DUF2442 domain-containing protein	-
MQE22_RS13740 (MQE22_13735)	9252..11336	+	2085	WP_255790339.1	methyltransferase domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..14321	14321
	-	flank	IS/Tn	-	-	11385..12440	1055

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (6-81)

Antitoxin

• Ribbon-helix-helix protein, CopG (34-72)

Sequences

Toxin

Protein

• Length: 91 a.a.
• Molecular weight: 10361.67 Da
• Isoelectric Point: 4.9059

>T239781 WP_255790356.1 NZ_CP094360:c7329-7057 [Acidithiobacillus sp. YTS05]
MGSFEFDEGKSCSNLEKHGIDFYEAQAIWKDDRRIEVPAKTVDEPRSMVIGRIGQKVWSAVVTPRGDNVRLISVSRARRE
EIELYESFDL

Nucleotide

• Length: 273 bp

>T239781 NZ_LS483318:c272801-272547 [Streptococcus dysgalactiae subsp. equisimilis]
ATGTTTAATTGTACTGAAGAGGCTTGGGAAGATTACACTTCTTGGCAAAGAGAAGATAAAAAAATTCTCAAGCGTATTAA
TCGACTGATTGAAGATATCAAACGTCACCCTTTCGAAGGAATCGGAAAACCAGAACCTTTAAAATATCGGTATTCTGGTG
CCTGGTCTCGCCGTATTACAGACGAACACCGTCTCGTTTATACGGTAGAACAAAATGATATCTATTTCTTATCTTTTAGA
GATCACTATAAGTAA

Antitoxin

Protein

• Length: 77 a.a.
• Molecular weight: 8742.94 Da
• Isoelectric Point: 6.3334

>AT239781 WP_255790354.1 NZ_CP094360:c7076-6846 [Acidithiobacillus sp. YTS05]
MKASTFDDRFDAGESVLDSLDLSKASRPDLEVRRVNVDLPEWMIRSLDQEARRLGVTRQSIIKVWVADRLEKRPAS

Nucleotide

• Length: 231 bp

>AT239781 NZ_LS483318:c273060-272794 [Streptococcus dysgalactiae subsp. equisimilis]
ATGGAAGCTGTTGTTTATTCAAATTTTAGAAACAATTTAAAAGATTACATGAAAAAGGTAAATGATGAATACGAGCCATT
AATGGTAGTTAATAAAAACCCTGAAGAAAATATCGTGGTCTTGTCTAAAGACAATTGGGATAGTATTCAAGAAACCATTC
GTATCATGAATAACGAATACCTCTCTGATAAAGTTCTATCAGGATTGGAACAAGTCAAACAAAAGAAAGTGACCCAACAC
CAATTATTAGAGGTGGAAGATGTTTAA