Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relE/YoeB-YefM
Location 647384..647886 Replicon chromosome
Accession NZ_CP094359
Organism Acidithiobacillus sp. YTS05

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag MQE22_RS03250 Protein ID WP_215870924.1
Coordinates 647632..647886 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag MQE22_RS03245 Protein ID WP_215870923.1
Coordinates 647384..647635 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MQE22_RS03230 (MQE22_03230) 644657..645058 + 402 WP_215870920.1 RidA family protein -
MQE22_RS03235 (MQE22_03235) 645045..645257 + 213 WP_215870921.1 DUF1858 domain-containing protein -
MQE22_RS03240 (MQE22_03240) 645262..647313 + 2052 WP_215870922.1 ATP-dependent DNA helicase RecG -
MQE22_RS03245 (MQE22_03245) 647384..647635 + 252 WP_215870923.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
MQE22_RS03250 (MQE22_03250) 647632..647886 + 255 WP_215870924.1 Txe/YoeB family addiction module toxin Toxin
MQE22_RS03255 (MQE22_03255) 647989..648795 + 807 WP_255790099.1 L,D-transpeptidase -
MQE22_RS03260 (MQE22_03260) 648800..650104 - 1305 WP_215870925.1 GGDEF domain-containing protein -
MQE22_RS03265 (MQE22_03265) 650220..651527 - 1308 WP_215870926.1 protoporphyrinogen oxidase -
MQE22_RS03270 (MQE22_03270) 651531..652586 - 1056 WP_215870927.1 AI-2E family transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10160.64 Da        Isoelectric Point: 10.0404

>T239774 WP_215870924.1 NZ_CP094359:647632-647886 [Acidithiobacillus sp. YTS05]
VRLVFSEQAWEDYLYWQKTDKKLVKRINDLIKENTRTPHSGVGKPESLKHALAGYWSRRINDEHRIVYKTMNDSILIVQL
RYHY

Download         Length: 255 bp

>T239774 NZ_LS483317:1900961-1901056 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCGCCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9257.55 Da        Isoelectric Point: 5.1297

>AT239774 WP_215870923.1 NZ_CP094359:647384-647635 [Acidithiobacillus sp. YTS05]
MDAITYSTARAKLADTMDRVCDDHEPIIITRNGEQAVVMMSLEDFKALEETSYLLRSPKNAKRLLESIASLESGRGKARN
LAE

Download         Length: 252 bp

>AT239774 NZ_LS483317:c1901141-1901084 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References