Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 2942259..2942805 Replicon chromosome
Accession NZ_CP094358
Organism Abyssalbus ytuae strain MT3330

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag MQE35_RS12445 Protein ID WP_255841750.1
Coordinates 2942259..2942537 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag MQE35_RS12450 Protein ID WP_255841751.1
Coordinates 2942545..2942805 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MQE35_RS12425 (MQE35_12405) 2939565..2940428 - 864 WP_255841742.1 alpha/beta fold hydrolase -
MQE35_RS12430 (MQE35_12410) 2940442..2940933 - 492 WP_255841744.1 DUF192 domain-containing protein -
MQE35_RS12435 (MQE35_12415) 2940936..2941892 - 957 WP_255841746.1 prolipoprotein diacylglyceryl transferase -
MQE35_RS12440 (MQE35_12420) 2941965..2942189 - 225 WP_255841748.1 membrane protein insertion efficiency factor YidD -
MQE35_RS12445 (MQE35_12425) 2942259..2942537 - 279 WP_255841750.1 Txe/YoeB family addiction module toxin Toxin
MQE35_RS12450 (MQE35_12430) 2942545..2942805 - 261 WP_255841751.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
MQE35_RS12455 (MQE35_12435) 2942928..2944412 - 1485 WP_255841753.1 cysteine--tRNA ligase -
MQE35_RS12460 (MQE35_12440) 2944434..2945120 - 687 WP_255841754.1 GTP cyclohydrolase I FolE -
MQE35_RS12465 (MQE35_12445) 2945258..2946775 - 1518 WP_255841755.1 outer membrane protein transport protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10841.61 Da        Isoelectric Point: 10.0807

>T239771 WP_255841750.1 NZ_CP094358:c2942537-2942259 [Abyssalbus ytuae]
MNIDFTAYGWKDFTYWLENDIDTALKIKELIKAIKQNPFKGIGKPEPLKHGLKGFWSRRINGEHRLVYQVSGKKGVDQKC
IIIQCRFHYDNK

Download         Length: 279 bp

>T239771 NZ_LS483317:345054-345305 [Staphylococcus aureus]
ATGAATAACCGCGAACAAATTGAACAGTCCGTTATAAGTGCTAGTGCGTATAACGGTAATGACACAGAGGGATTACTAAA
AGAGATTGAGGACGTGTATAAGAAAGCGCGAGCGTTTGATGAAATACTTGAGGGAATGACAAATGCTATTCAACATTCAG
TTAGAGAAGGTATTGAACTTGATGAAGCAGTAGGGATTATGGCAGGTCAAGTGGTCTATAAATATGAGGAGGAACAGGAA
AATGAGTATTAG

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9832.19 Da        Isoelectric Point: 7.2018

>AT239771 WP_255841751.1 NZ_CP094358:c2942805-2942545 [Abyssalbus ytuae]
MRAITISTLRKNIKKHFDYVSKSSEIIVVPRSKGDDAVVIMSINEYNSLKETEHLLSTKANRTRLMDSIEQIDKGELVSY
NETTTE

Download         Length: 261 bp

>AT239771 NZ_LS483317:345295-345468 [Staphylococcus aureus]
ATGAGTATTAGTGTAGGAGATAAAGTATATAACCATGAAACAAACGAAAGTCTAGAGATTGTGCAATTGGTCGGAGATAT
TAGAGATACACATTATAAACTGTCCGATGATTCAGTTATTAGCATTATAGATTTTATTACTAAACCAATTTATCTAATTA
AAGGGGACGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References