239768

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 5104476..5106211 Replicon chromosome
Accession NZ_CP094351
Organism Pseudomonas orientalis strain YB-76

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag MRY17_RS22815 Protein ID WP_181283096.1
Coordinates 5104476..5105120 (+) Length 215 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag MRY17_RS22820 Protein ID WP_181283095.1
Coordinates 5105117..5106211 (+) Length 365 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MRY17_RS22785 (MRY17_22785) 5099781..5100437 + 657 WP_057724876.1 DedA family protein -
MRY17_RS22790 (MRY17_22790) 5100443..5101258 + 816 WP_243352910.1 zinc-dependent peptidase -
MRY17_RS22795 (MRY17_22795) 5101368..5101895 + 528 WP_005791810.1 inorganic diphosphatase -
MRY17_RS22800 (MRY17_22800) 5102107..5102877 + 771 WP_191953281.1 helix-turn-helix transcriptional regulator -
MRY17_RS22805 (MRY17_22805) 5103154..5103405 - 252 WP_181283098.1 hypothetical protein -
MRY17_RS22810 (MRY17_22810) 5103907..5104479 + 573 WP_181283097.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
MRY17_RS22815 (MRY17_22815) 5104476..5105120 + 645 WP_181283096.1 DUF4433 domain-containing protein Toxin
MRY17_RS22820 (MRY17_22820) 5105117..5106211 + 1095 WP_181283095.1 macro domain-containing protein Antitoxin
MRY17_RS22825 (MRY17_22825) 5106428..5106657 - 230 Protein_4489 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
MRY17_RS22830 (MRY17_22830) 5106647..5107411 - 765 WP_243352911.1 type IV toxin-antitoxin system AbiEi family antitoxin -
MRY17_RS22835 (MRY17_22835) 5107620..5108252 + 633 WP_034117703.1 isochorismate family cysteine hydrolase YcaC -
MRY17_RS22840 (MRY17_22840) 5108400..5109539 + 1140 WP_243352912.1 Fic family protein -
MRY17_RS22845 (MRY17_22845) 5109615..5109857 + 243 WP_003176346.1 exodeoxyribonuclease VII small subunit -
MRY17_RS22850 (MRY17_22850) 5109854..5110741 + 888 WP_243352913.1 polyprenyl synthetase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(14-213)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 215 a.a.        Molecular weight: 24889.44 Da        Isoelectric Point: 6.6552

>T239768 WP_181283096.1 NZ_CP094351:5104476-5105120 [Pseudomonas orientalis]
MIYNNLNPEKALIWRIVHRDNLPWILDNGLHCASSEVQAAQYVDIGNVDLIDKRRTRCVPIAPSGFLSDYVPFYFTPFSV
MMKNIHSGWSVQRRNNDEIVILVSSLHRVAELGLPFVFTNAHAYPDWTDYYSDLANLHEIDWSILQRRDFKRDPDDPRKM
ERYQAEALIHHHLPITGLLGIMCYTDAMKERIEQDVAARGLTLPVHARPGWYFP

Download         Length: 645 bp

>T239768 NZ_LS483316:c2521566-2521300 [Staphylococcus aureus]
ATGGCTAGGTTAAATATTACGTTTTCGCCTCAAGCCTTTGAAGATTATAAGTATTTTCAGCAGAACGATAAAAAAATGGT
GAAGAAGATTAATGAGTTACTTAAAAGTATTGACAGAAATGGTGCATTGGAAGGTATAGGTAAGCCTGAAAAGTTAAAAT
CGAATCTGACTGGGTATTATAGTAGACGTATCAATCACGAACATAGATTGGTTTATACAGTAGATGACAATCATATAAAA
ATAGCATCATGTAAATACCATTATTAA

Antitoxin


Download         Length: 365 a.a.        Molecular weight: 41192.23 Da        Isoelectric Point: 6.9072

>AT239768 WP_181283095.1 NZ_CP094351:5105117-5106211 [Pseudomonas orientalis]
MIRFTQGNLLQANAEVLVNTVNTVGVMGKGIALMFKERFAENYRLYAAACKAGEVETGKVHVTAVNELDGPRWIVNFPTK
RHWRSPSQMAWITEGLHDLRRFLIENHVKSVAVPPLGAGNGGLKWPDVREQIEDVLSDLDVDVLVFEPSNQYLNVAKRSG
VEQLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERAIEKRPGLKNPLDLKFVAHKYGPYANRLEHLLNNLDGSYLH
CDKRISDAENSDVIWFDQDRRAFLQTYLRTQAKEYSQALELTAELIDGFESPFGMELLATVDWLLTQEDVAPTVPAVREA
LKRWNGGVAAAARKNKLFDDQALDIALKRLTSSSFSRQMTSCHI

Download         Length: 1095 bp

>AT239768 NZ_LS483316:c2521817-2521566 [Staphylococcus aureus]
ATGATTATTAAAAATTATTCATACGCTCGACAGAATTTAAAGGCACTTATGACAAAAGTAAATGATGATAGTGATATGGT
AACTGTAACATCTACTGATGATAAAAACGTAGTAATCATGTCAGAATCAGATTATAACTCCATGATGGAAACACTTTACC
TCCAACAGAACCCAAATAATGCTGAACACTTAGCTCAATCAATTGCAGATCTAGAACGTGGGAAAACTATAACGAAAGAT
ATAGATGTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References