239767

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 4425278..4425906 Replicon chromosome
Accession NZ_CP094351
Organism Pseudomonas orientalis strain YB-76

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag MRY17_RS19645 Protein ID WP_181284763.1
Coordinates 4425278..4425676 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag MRY17_RS19650 Protein ID WP_034135537.1
Coordinates 4425676..4425906 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MRY17_RS19615 (MRY17_19615) 4420429..4420698 + 270 WP_124433734.1 DUF2790 domain-containing protein -
MRY17_RS19620 (MRY17_19620) 4420848..4421081 - 234 WP_243352719.1 AbrB family transcriptional regulator -
MRY17_RS19625 (MRY17_19625) 4421464..4422714 + 1251 WP_243352720.1 ribonucleotide-diphosphate reductase subunit beta -
MRY17_RS19630 (MRY17_19630) 4423030..4423608 + 579 WP_181284765.1 Bro-N domain-containing protein -
MRY17_RS19635 (MRY17_19635) 4423708..4424421 + 714 WP_243352721.1 HNH endonuclease signature motif containing protein -
MRY17_RS19640 (MRY17_19640) 4424494..4425141 + 648 WP_124360550.1 HAD-IB family hydrolase -
MRY17_RS19645 (MRY17_19645) 4425278..4425676 - 399 WP_181284763.1 tRNA(fMet)-specific endonuclease VapC Toxin
MRY17_RS19650 (MRY17_19650) 4425676..4425906 - 231 WP_034135537.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
MRY17_RS19655 (MRY17_19655) 4426226..4427185 - 960 WP_181284762.1 LysR family transcriptional regulator -
MRY17_RS19660 (MRY17_19660) 4427379..4428806 + 1428 WP_243352722.1 argininosuccinate lyase -
MRY17_RS19665 (MRY17_19665) 4428913..4429791 + 879 WP_181284760.1 amino acid ABC transporter permease -
MRY17_RS19670 (MRY17_19670) 4429816..4430580 + 765 WP_065887758.1 amino acid ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 15024.25 Da        Isoelectric Point: 8.0474

>T239767 WP_181284763.1 NZ_CP094351:c4425676-4425278 [Pseudomonas orientalis]
MLKFMLDTNICIFTIKNRPQQVRETFRKHYGQLAISTVTLMELIYGAEKSPNPERNLADVEGFAARLEVLKYDQDAAMHT
GQLRAELARAGTPIGSYDQMIAGHARSQGLIMVTNNRREFDRVPGLRVEDWV

Download         Length: 399 bp

>T239767 NZ_LS483316:c2256565-2256461 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8467.28 Da        Isoelectric Point: 4.2404

>AT239767 WP_034135537.1 NZ_CP094351:c4425906-4425676 [Pseudomonas orientalis]
MDQGSVFQSNRSQAVRLPKAAALPDDVKRVDVVSIGRARIITPAGESWDSWFDGEGVTPDFMNDRDQPADQERESF

Download         Length: 231 bp

>AT239767 NZ_LS483316:2256367-2256405 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References