Detailed information of TA system TA239765

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/-
• Location: 3695204..3696422
• Replicon: chromosome
• Accession: NZ_CP094351
• Organism: Pseudomonas orientalis strain YB-76

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: MRY17_RS16315
• Protein ID: WP_181285254.1
• Coordinates: 3695850..3696422 (+)
• Length: 191 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: MRY17_RS16310
• Protein ID: WP_191951993.1
• Coordinates: 3695204..3695761 (+)
• Length: 186 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MRY17_RS16280 (MRY17_16280)	3690694..3690936	+	243	WP_181285262.1	hypothetical protein	-
MRY17_RS16285 (MRY17_16285)	3691089..3692294	+	1206	WP_243352492.1	DUF1835 domain-containing protein	-
MRY17_RS16290 (MRY17_16290)	3692298..3692717	-	420	WP_243352493.1	chemotaxis protein CheY	-
MRY17_RS16295 (MRY17_16295)	3692890..3693726	+	837	WP_243352494.1	HAD family acid phosphatase	-
MRY17_RS16300 (MRY17_16300)	3693752..3694525	-	774	WP_181285257.1	OmpA family protein	-
MRY17_RS16305 (MRY17_16305)	3694536..3694928	-	393	WP_181285256.1	DUF4398 domain-containing protein	-
MRY17_RS16310 (MRY17_16310)	3695204..3695761	+	558	WP_191951993.1	helix-turn-helix transcriptional regulator	Antitoxin
MRY17_RS16315 (MRY17_16315)	3695850..3696422	+	573	WP_181285254.1	HD domain-containing protein	Toxin
MRY17_RS16320 (MRY17_16320)	3696425..3696652	-	228	Protein_3221	Rid family hydrolase	-
MRY17_RS16325 (MRY17_16325)	3696929..3697183	-	255	WP_124433323.1	DUF6124 family protein	-
MRY17_RS16330 (MRY17_16330)	3697517..3699736	-	2220	WP_243352495.1	type II secretion system secretin GspD	-
MRY17_RS16335 (MRY17_16335)	3699733..3700257	-	525	WP_243352496.1	general secretion pathway protein GspN	-
MRY17_RS16340 (MRY17_16340)	3700254..3700865	-	612	WP_057721904.1	type II secretion system protein GspM	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• 5'-deoxynucleotidase YfbR/HDDC2 (9-184)

Antitoxin

• Cro/C1-type helix-turn-helix domain (12-64)

Sequences

Toxin

Protein

• Length: 191 a.a.
• Molecular weight: 21281.31 Da
• Isoelectric Point: 4.7389

>T239765 WP_181285254.1 NZ_CP094351:3695850-3696422 [Pseudomonas orientalis]
MDFEKIKGRLDFLREAEKLKDVLRSAHTASGRTESTAEHSWRLCLMAMVFADQLPGLDLLKILKMCVIHDLGEAINGDIP
AVSQAAFPDKGEQERRDLLLLTQTLDGALKTQIMALWDDYENALSPEAKAVKAMDKLETLLQHTQGLNPPDFDYAFNLAY
GKKHTDAEPLFEALRALIDRATQERLDAGD

Nucleotide

• Length: 573 bp

>T239765 NZ_LS483316:c2179598-2179236 [Staphylococcus aureus]
ATGATTAGACGAGGAGATGTTTATTTAGCAGATTTATCACCAGTACAGGGATCTGAACAAGGGGGAGTCAGACCTGTAGT
CATAATTCAAAATGATACTGGTAATAAATATAGTCCTACAGTTATTGTTGCGGCAATAACTGGTAGGATTAATAAAGCGA
AAATACCGACACATGTAGAGATTGAAAAGAAAAAGTATAAGTTGGATAAAGACTCAGTTATATTATTAGAACAAATTCGT
ACACTTGATAAAAAACGATTGAAAGAAAAACTGACGTACTTATCCGATGATAAAATGAAAGAAGTAGATAATGCACTAAT
GATTAGTTTAGGGCTGAATGCAGTAGCTCACCAGAAAAATTAG

Antitoxin

Protein

• Length: 186 a.a.
• Molecular weight: 20415.47 Da
• Isoelectric Point: 10.9658

>AT239765 WP_191951993.1 NZ_CP094351:3695204-3695761 [Pseudomonas orientalis]
MPALILQPAIPGIALRRWRVLHRVKQTHAAQMFNVNQSTLSRWENGVQAMDAAAHQQLERLLSARLDSAADQALAGLVRE
SPRAVHLVCDLTHRLLACSPSRAAQFSRPLVDLTGQSLWRYATPQIRQAEAALDHTGWRDTQAPPALQFCTGSNGSSLVP
IRPSLCRWTRMILSDGSAARLVETL

Nucleotide

• Length: 558 bp

>AT239765 NZ_LS483316:c2179765-2179595 [Staphylococcus aureus]
ATGTTATCTTTTAGTCAAAATAGAAGTCATAGCTTAGAACAATCTTTAAAAGAAGGATATTCACAAATGGCTGATTTAAA
TCTCTCCCTAGCGAACGAAGCTTTTCCGATAGAGTGTGAAGCATGCGATTGCAACGAAACATATTTATCTTCTAATTCAA
CGAATGAATGA