Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 1596015..1596531 Replicon chromosome
Accession NZ_CP094351
Organism Pseudomonas orientalis strain YB-76

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MRY17_RS07010 Protein ID WP_181283940.1
Coordinates 1596015..1596302 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MRY17_RS07015 Protein ID WP_057723048.1
Coordinates 1596292..1596531 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MRY17_RS06980 (MRY17_06980) 1591425..1591985 - 561 WP_181283936.1 glycine cleavage system protein R -
MRY17_RS06985 (MRY17_06985) 1592248..1593126 + 879 WP_181283937.1 4-hydroxy-tetrahydrodipicolinate synthase -
MRY17_RS06990 (MRY17_06990) 1593144..1594259 + 1116 WP_181283938.1 outer membrane protein assembly factor BamC -
MRY17_RS06995 (MRY17_06995) 1594264..1595022 + 759 WP_243353482.1 MBL fold metallo-hydrolase -
MRY17_RS07000 (MRY17_07000) 1595050..1595763 + 714 WP_057723050.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
MRY17_RS07010 (MRY17_07010) 1596015..1596302 - 288 WP_181283940.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MRY17_RS07015 (MRY17_07015) 1596292..1596531 - 240 WP_057723048.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
MRY17_RS07020 (MRY17_07020) 1597235..1598461 - 1227 WP_181283941.1 MFS transporter -
MRY17_RS07025 (MRY17_07025) 1598622..1598993 - 372 WP_124357461.1 transcriptional regulator -
MRY17_RS07030 (MRY17_07030) 1598997..1599299 - 303 WP_057723044.1 type II toxin-antitoxin system HigB family toxin -
MRY17_RS07035 (MRY17_07035) 1599601..1601226 + 1626 WP_191951408.1 methyl-accepting chemotaxis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-71)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11179.87 Da        Isoelectric Point: 10.2270

>T239762 WP_181283940.1 NZ_CP094351:c1596302-1596015 [Pseudomonas orientalis]
MTYSLDFDARALKEWQKLGDTLRQQFKKKLAKILNNPRNEANRLHGLPDCYKIKLRSSGYRLVYQVIDQEITVVVVAVDK
REHDQAYRKATDRLS

Download         Length: 288 bp

>T239762 NZ_LS483316:1868521-1868616 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8973.39 Da        Isoelectric Point: 4.6017

>AT239762 WP_057723048.1 NZ_CP094351:c1596531-1596292 [Pseudomonas orientalis]
MASINVRIDDDLKARAYLELEKLGVTPSELMRQALQYVAERGQLPFKPVLMTEEDEALMATVRERLASPQRVKVSLDDL

Download         Length: 240 bp

>AT239762 NZ_LS483316:c1868703-1868644 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References