239644

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DhiAT/dnstrm_HI1420(antitoxin)
Location 1803791..1804570 Replicon chromosome
Accession NZ_CP094323
Organism Edwardsiella anguillarum strain 43472

Toxin (Protein)


Gene name dhiT Uniprot ID -
Locus tag MQ087_RS08350 Protein ID WP_198077053.1
Coordinates 1804313..1804570 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name dhiA Uniprot ID -
Locus tag MQ087_RS08345 Protein ID WP_283294710.1
Coordinates 1803791..1804303 (-) Length 171 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MQ087_RS08315 (MQ087_08305) 1798916..1800298 + 1383 WP_283294703.1 replicative DNA helicase -
MQ087_RS08320 (MQ087_08310) 1800326..1800673 + 348 WP_283294704.1 hypothetical protein -
MQ087_RS08325 (MQ087_08315) 1800783..1801427 + 645 WP_034165085.1 DUF1367 family protein -
MQ087_RS08330 (MQ087_08320) 1801430..1801729 + 300 WP_283294705.1 DUF1364 family protein -
MQ087_RS08335 (MQ087_08325) 1801874..1802914 + 1041 WP_283294706.1 hypothetical protein -
MQ087_RS08340 (MQ087_08330) 1802915..1803424 + 510 WP_071525693.1 hypothetical protein -
MQ087_RS08345 (MQ087_08335) 1803791..1804303 - 513 WP_283294710.1 DUF2442 domain-containing protein Antitoxin
MQ087_RS08350 (MQ087_08340) 1804313..1804570 - 258 WP_198077053.1 DUF4160 domain-containing protein Toxin
MQ087_RS08355 (MQ087_08345) 1804940..1805710 + 771 WP_283294713.1 Rha family transcriptional regulator -
MQ087_RS08360 (MQ087_08350) 1805832..1806347 + 516 WP_034165088.1 hypothetical protein -
MQ087_RS08365 (MQ087_08355) 1806436..1807254 + 819 WP_283294714.1 hypothetical protein -
MQ087_RS08370 (MQ087_08360) 1807488..1807886 + 399 WP_144242831.1 hypothetical protein -
MQ087_RS08375 (MQ087_08365) 1808003..1808233 + 231 WP_034165090.1 ParD-like family protein -
MQ087_RS08380 (MQ087_08370) 1808208..1808537 + 330 WP_283294715.1 type II toxin-antitoxin system RelE/ParE family toxin -
MQ087_RS08385 (MQ087_08375) 1808623..1808970 + 348 WP_283294716.1 phage holin, lambda family -
MQ087_RS08390 (MQ087_08380) 1808973..1809524 + 552 WP_283294717.1 glycosyl hydrolase 108 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1780993..1826412 45419


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Protein of unknown function DUF4160

(9-74)

Antitoxin

Uncharacterized protein HI1420

(82-161)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9625.29 Da        Isoelectric Point: 7.4665

>T239644 WP_198077053.1 NZ_CP094323:c1804570-1804313 [Edwardsiella anguillarum]
MPEIDALMGLSFVMYFFDNQTHSLPHVHVKYGEFELVIGIDSGEALEGYLPPKKRKLAESHIKANKTRLLAMWQMAVNGM
HPGKL

Download         Length: 258 bp

>T239644 NZ_LS483297:738480-738776 [Escherichia coli]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCACTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA

Antitoxin


Download         Length: 171 a.a.        Molecular weight: 18249.67 Da        Isoelectric Point: 7.3201

>AT239644 WP_283294710.1 NZ_CP094323:c1804303-1803791 [Edwardsiella anguillarum]
MLKIIDVDVVGDHVIEVEFSDGFRGRADLTALFSKPPFSAIADFNRFSLTASGVLNWGDAELSADTVRRMSKGAVVSASS
RSLMPENVEAILRQATWESMSEGRPDILQAALRGYAEQLGHADVIKRAGIASRSSAYKTLSPSTNPSFKSLAKISGAILA
IVRENNAQHG

Download         Length: 513 bp

>AT239644 NZ_LS483297:738778-739173 [Escherichia coli]
ATGAAATGTCCGGTTTGCCACCAGGGAGAAATGGTTTCTGGCATTAAAGATATTCCATACACCTTCCGTGGACGAAAAAC
AGTATTGAAAGGTATCCACGGTTTATATTGTGTCCATTGCGAAGAGAGCATCATGAATAAAGAAGAGTCAGATGCTTTCA
TGGCGCAAGTAAAGGCATTTCGGGCTTCGGTGAATGCCGAAACAGTGGCACCTGAATTTATAGTGAAGGTTCGAAAAAAG
CTCTCTCTTACCCAAAAAGAGGCAAGCGAAATTTTTGGGGGAGGTGTAAATGCGTTTTCGCGTTACGAAAAAGGCAATGC
CCAACCTCATCCTTCCACAATCAAACTTTTACGTGTTCTGGATAAGCATCCAGAACTATTGAATGAAATCCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References