Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) Hha-TomB/-
Location 1116742..1117334 Replicon chromosome
Accession NZ_CP094321
Organism Edwardsiella anguillarum strain 43473

Toxin (Protein)


Gene name Hha Uniprot ID D0ZEC2
Locus tag MQ094_RS05080 Protein ID WP_012847872.1
Coordinates 1116742..1116945 (-) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID A0A034T4H2
Locus tag MQ094_RS05085 Protein ID WP_034163649.1
Coordinates 1116966..1117334 (-) Length 123 a.a.

Genomic Context


MQ094_RS05070MQ094_RS05075MQ094_RS05060MQ094_RS05065MQ094_RS05080MQ094_RS05085MQ094_RS05090MQ094_RS05095
Location: 1115177..1115797 (621 bp)
Type: Others
Protein ID: WP_001267012.1
Location: 1116015..1116242 (228 bp)
Type: Others
Protein ID: WP_024183738.1
Location: 1112030..1113742 (1713 bp)
Type: Others
Protein ID: WP_174490643.1
Location: 1113739..1114791 (1053 bp)
Type: Others
Protein ID: WP_032082908.1
Location: 1116742..1116945 (204 bp)
Type: Toxin
Protein ID: WP_012847872.1
Location: 1116966..1117334 (369 bp)
Type: Antitoxin
Protein ID: WP_034163649.1
Location: 1117701..1120853 (3153 bp)
Type: Others
Protein ID: WP_034163648.1
Location: 1120897..1122081 (1185 bp)
Type: Others
Protein ID: WP_034163646.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
MQ094_RS05060 (MQ094_05065)1112030..1113742-1713WP_174490643.1hypothetical protein-
MQ094_RS05065 (MQ094_05070)1113739..1114791-1053WP_032082908.1nucleoid-associated protein-
MQ094_RS05070 (MQ094_05075)1115177..1115797+621WP_001267012.1recombinase family protein-
MQ094_RS05075 (MQ094_05080)1116015..1116242+228WP_024183738.1DUF2188 domain-containing protein-
MQ094_RS05080 (MQ094_05085)1116742..1116945-204WP_012847872.1HHA domain-containing proteinToxin
MQ094_RS05085 (MQ094_05090)1116966..1117334-369WP_034163649.1Hha toxicity modulator TomBAntitoxin
MQ094_RS05090 (MQ094_05095)1117701..1120853-3153WP_034163648.1efflux RND transporter permease subunit-
MQ094_RS05095 (MQ094_05100)1120897..1122081-1185WP_034163646.1efflux RND transporter periplasmic adaptor subunit-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(8-64)

Antitoxin

(1-115)


Sequences


Toxin        


Download         Length: 68 a.a.        Molecular weight: 8103.37 Da        Isoelectric Point: 5.0914

>T239619 WP_012847872.1 NZ_CP094321:c1116945-1116742 [Edwardsiella anguillarum]
MTKIDYLMKLRKCTTLDTLERVIEKNKYELSDDELEIFYSAADHRLAELTMNKLYDKIPAEVWQYVR

Download         Length: 204 bp

>T239619 NZ_LS483258:1310030-1311370 [Bordetella pertussis]
ATGGGGCGCCGATCGCACAGCCGCAGCCTGTCCATCTGGACCAACGGCGTTCGCGTCGGGCGTTGGACGGTTCCCGCTCG
CGGAGAGATGGAACTGCAGTACGACGTGGATTGGGTCCGTGCCGACGTCGGCCGGCCACTTTCGCTGTCGCTGCCATTCA
ACTTGCAGAATCTGCCCCTCAAGGGGGAGAGAGTCGCCAACTACTTCGACAATCTGCTACCGGACAGCGACGCTATCCGT
CGTCGCGTGGCCGAGCGATTCAGGACGGGCTCGGTCGATCCCTTCGATCTGTTGAAAGCCATTGGACGCGATTGCGTTGG
CGCCGTACAGATCCTGGAAGACGAAGAGATACCTGAGGGCTTTGATCGCATCGAGGGCGTGCCTCTGTCCGAGGAGGACA
TCGAGCGGCATTTGATCGAAACCGTTACGCCGCGCGCCTTCGCTGCGGGCCGGGACCCGGACGCGGATTTCAGAATTTCT
CTGGCCGGCGCGCAAGAGAAGACAGCCTTCCTGTGGTGGGGCGGACAGTGGCTTGCGCCGCGTGGCGCGACATCGACGAG
CCATATTTTCAAACTTCCATTGGGCTTGGTGGGTGGACGGCGGGCTGACTTCAGCACTTCTGTTGATAACGAATGGCTGT
GTCTGAAGCTGCTGAAGGCGTATGGGTTGGATGTGGCTGAGGCCAGCATCGCAACCTTCGGACAGCAGCGAGTGCTGGTG
GTCGAGCGATTCGACCGGCGTGTTGCGCCCAACGGGCAATGGCTGATGCGCCTGCCGCAGGAAGATTTCTGCCAGGTCGA
GGGGTGCTCGCCGCTACGCAAGTATGAAAACGAGGGCGGCCCAGGACTCAAGGCCTTATTCGCCACGCTGCGGCAGTCAG
TGAACGCAGCGGTCGATATGAGAACGTTGATGGCGGCGCAGATCCTGTTTTGGTTGCTGCGGGCACCCGATGGCCACGCC
AAGAATTTCAGCATCCAGTTGTTGCCGCGCGGCCGTTTCCAGTTGACTAGACTGTACGACGTGATGTCGGCCTATCCGGT
ACTGGGCGATGGCGCGAATCAGTGGTCGCCGTTCGAAATCAAATTGGCGATGGCATTGATTGGCAAGAACCGGCATTACG
AGATGCACGGCATCCAGCGCAGGCACTTCAACAGCACCGCACAAAAAGTTGGTTATGGCCCGACGGCGGAGCCGATCATT
GAAGACCTGTTGGCCCGTACGCCCGCGATCATTGCCGCCGTGCAGGCCGATTTGCCGCAGGACTTCTCGCCGCGTGTTGC
GGACTCCGTCCTGGGTGGGCTTGCGCAGGCCGCAAAGTCGCTCGGCGCAATGATGCCGTAA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14118.85 Da        Isoelectric Point: 6.2108

>AT239619 WP_034163649.1 NZ_CP094321:c1117334-1116966 [Edwardsiella anguillarum]
MDEYTSYQHDIAELKYLCDSLYHQGIDVLGESHHGWVSDPTAKVNLQLNELIEHIASVAQSFKIKYPRHSDLAEILDDYL
DETYALFGAYSVSETALRHWLRTKRRVAYCLAHEKRNAALHV

Download         Length: 369 bp

>AT239619 NZ_LS483258:1309771-1310028 [Bordetella pertussis]
ATGCCGCCGCCATCACAACCTCTGCTCACTACCGGCCAGCTTGGCGCGGTCTTGCAGGCTGCACGCAAAGCACAGGGACT
GACTCAATCGGCCCTGGCCAGTCGTATCGGCCTGAGCCAATCGCGGGTCTCGCACCTGGAGTTGAATGCCCATCAACTGA
GCGTGGAGCAGCTCCTGGCCTGGTGCGCGGCGCTAGGGTTGGAGTTGACGATTGCGACTCGCGGAAGTCCCGCAGGGTCT
TCCGACGCGGATTGGTGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
AlphaFold DBA0A034SMG4


Antitoxin

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Source
ID
Structure
AlphaFold DBA0A034T4H2

References