239596

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DhiAT/dnstrm_HI1420(antitoxin)
Location 1809223..1810002 Replicon chromosome
Accession NZ_CP094319
Organism Edwardsiella anguillarum strain 43651

Toxin (Protein)


Gene name dhiT Uniprot ID -
Locus tag MQ085_RS08390 Protein ID WP_198077053.1
Coordinates 1809745..1810002 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name dhiA Uniprot ID -
Locus tag MQ085_RS08385 Protein ID WP_283294710.1
Coordinates 1809223..1809735 (-) Length 171 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MQ085_RS08355 (MQ085_08345) 1804348..1805730 + 1383 WP_283294703.1 replicative DNA helicase -
MQ085_RS08360 (MQ085_08350) 1805758..1806105 + 348 WP_283294704.1 hypothetical protein -
MQ085_RS08365 (MQ085_08355) 1806215..1806859 + 645 WP_034165085.1 DUF1367 family protein -
MQ085_RS08370 (MQ085_08360) 1806862..1807161 + 300 WP_283294705.1 DUF1364 family protein -
MQ085_RS08375 (MQ085_08365) 1807306..1808346 + 1041 WP_283294706.1 hypothetical protein -
MQ085_RS08380 (MQ085_08370) 1808347..1808856 + 510 WP_071525693.1 hypothetical protein -
MQ085_RS08385 (MQ085_08375) 1809223..1809735 - 513 WP_283294710.1 DUF2442 domain-containing protein Antitoxin
MQ085_RS08390 (MQ085_08380) 1809745..1810002 - 258 WP_198077053.1 DUF4160 domain-containing protein Toxin
MQ085_RS08395 (MQ085_08385) 1810372..1811142 + 771 WP_283294713.1 Rha family transcriptional regulator -
MQ085_RS08400 (MQ085_08390) 1811264..1811779 + 516 WP_034165088.1 hypothetical protein -
MQ085_RS08405 (MQ085_08395) 1811868..1812686 + 819 WP_283294714.1 hypothetical protein -
MQ085_RS08410 (MQ085_08400) 1812920..1813318 + 399 WP_144242831.1 hypothetical protein -
MQ085_RS08415 (MQ085_08405) 1813435..1813665 + 231 WP_034165090.1 ParD-like family protein -
MQ085_RS08420 (MQ085_08410) 1813640..1813969 + 330 WP_283294715.1 type II toxin-antitoxin system RelE/ParE family toxin -
MQ085_RS08425 (MQ085_08415) 1814055..1814402 + 348 WP_283294716.1 phage holin, lambda family -
MQ085_RS08430 (MQ085_08420) 1814405..1814956 + 552 WP_283294717.1 glycosyl hydrolase 108 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1786419..1836439 50020


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Protein of unknown function DUF4160

(9-74)

Antitoxin

Uncharacterized protein HI1420

(82-161)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9625.29 Da        Isoelectric Point: 7.4665

>T239596 WP_198077053.1 NZ_CP094319:c1810002-1809745 [Edwardsiella anguillarum]
MPEIDALMGLSFVMYFFDNQTHSLPHVHVKYGEFELVIGIDSGEALEGYLPPKKRKLAESHIKANKTRLLAMWQMAVNGM
HPGKL

Download         Length: 258 bp

>T239596 NZ_LS399318:c5045607-5044285 [Klebsiella pneumoniae]
ATGGCGACGCTTACCACCTGGATGAACAATGTGCGCGTGGGAACCTTAACCCGCCAGGCTAACGGGGCGCACAGTTTTCG
CTATGAGGAAGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCACTGCCGCTGCAGTATGGCAATATCACTG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGACCGGATCGTCAGGCGCTATCAG
GCGCGCTCGAAGCAGCCGTTCGATCTGCTGGCCGAAGTCGGGCGGGATAGCGTAGGGGCGGTGACCCTCCTGCCGCCGGG
GGAAGAGGCGCACCTGGAAGGATTACGCTGGCAGACGCTGGACGAGGCGCAGCTCACCGCTTTGCTGACCGCTTACCAGT
CGGATATCCCCCTCGGGATGATTACCAGCCAGGACGATTTCCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACGGCGCTG
CTGCGGATGGGCGAGCAGTGGTGTATTCCGCAGGGCGCCACGCCGACCACGCATATCATTAAGCTGCCCATCGGCGAGAT
AAAGCAGCCCAATGCGACGCTGGATCTGCGCGAAAGCGTGGATAATGAGTATCTGTGCCTGGCGCTGGCCAGAGAACTGG
GCCTGGCGGTGCCGGAAGCGGAGATCATCACCACCCCGCGGATCCGCGCCCTGGCGGTAACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGACGGGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCTTTTGGTCTTCCTTCAGCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCGAGTGAAGCGCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTCTTCCAGTGGCTGACGGGGGCGACGGACGGTCACGCAAAAAACTTCTCAATTTACCTGTTG
CCCGGCGGCAGCTACCGCTTAACACCGTTCTACGACATTATTTCGGCGTTTCCGGTGCTGGGCGGCACGGGACTGCATCT
GCGCGATCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGTAAAACAGAGATTAACGCCATCTATCCGCGTCATT
TTCTGGCGACGGCCAAAGCGGTGAACTTTCCCCGGGAGCAGATGCTGGCGATCCTCCAGGAGTTTGCCGGGCATGTGCCG
CAGGCAATCGAAAGCGCTCGCCGGACGCTGCCGGCGGACTTTTCCAGCCACGTCTGGCAGGCCATTACAGAGAACATGCT
GAAGCTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGCTATAG

Antitoxin


Download         Length: 171 a.a.        Molecular weight: 18249.67 Da        Isoelectric Point: 7.3201

>AT239596 WP_283294710.1 NZ_CP094319:c1809735-1809223 [Edwardsiella anguillarum]
MLKIIDVDVVGDHVIEVEFSDGFRGRADLTALFSKPPFSAIADFNRFSLTASGVLNWGDAELSADTVRRMSKGAVVSASS
RSLMPENVEAILRQATWESMSEGRPDILQAALRGYAEQLGHADVIKRAGIASRSSAYKTLSPSTNPSFKSLAKISGAILA
IVRENNAQHG

Download         Length: 513 bp

>AT239596 NZ_LS399318:c5045873-5045607 [Klebsiella pneumoniae]
ATGAATTCCCCGCAGATATACAGTCCCGTGCAGCTGGCCAATTACCTGAAGCTGCTGCGCCAGCAGAACCACTGGACCCA
GGATGCGCTGGCCAGGCGGATCGGCATTAAGCAGGCCACGCTGTCCAATTTTGAAAATCACCCCGACAAAACCACCTTAA
CCACGCTGTTTAAGATCCTCCAGTCGCTGGGGGTGGTGATGACGCTGAACGCCAAAGCTGCTGAGACGGCGCCGGCTCCC
GATAACAACACGGACCTTGACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References