Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3545226..3545889 Replicon chromosome
Accession NZ_CP094313
Organism Edwardsiella anguillarum strain R18-14-16

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag MQ086_RS16525 Protein ID WP_034164690.1
Coordinates 3545226..3545642 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID D0ZDY6
Locus tag MQ086_RS16530 Protein ID WP_012849755.1
Coordinates 3545623..3545889 (-) Length 89 a.a.

Genomic Context


MQ086_RS16520MQ086_RS16535MQ086_RS16550MQ086_RS16505MQ086_RS16510MQ086_RS16515MQ086_RS16525MQ086_RS16530MQ086_RS16540MQ086_RS16545
Location: 3544689..3545201 (513 bp)
Type: Others
Protein ID: WP_034164689.1
Location: 3546238..3547236 (999 bp)
Type: Others
Protein ID: WP_034164692.1
Location: 3549740..3550390 (651 bp)
Type: Others
Protein ID: WP_034164746.1
Location: 3541156..3542889 (1734 bp)
Type: Others
Protein ID: WP_034164685.1
Location: 3542894..3543610 (717 bp)
Type: Others
Protein ID: WP_034164686.1
Location: 3543638..3544537 (900 bp)
Type: Others
Protein ID: WP_034164688.1
Location: 3545226..3545642 (417 bp)
Type: Toxin
Protein ID: WP_034164690.1
Location: 3545623..3545889 (267 bp)
Type: Antitoxin
Protein ID: WP_012849755.1
Location: 3547278..3548102 (825 bp)
Type: Others
Protein ID: WP_034164693.1
Location: 3548259..3549131 (873 bp)
Type: Others
Protein ID: WP_034164695.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
MQ086_RS16505 (MQ086_16480)3541156..3542889-1734WP_034164685.1single-stranded-DNA-specific exonuclease RecJ-
MQ086_RS16510 (MQ086_16485)3542894..3543610-717WP_034164686.1bifunctional protein-disulfide isomerase/oxidoreductase DsbC-
MQ086_RS16515 (MQ086_16490)3543638..3544537-900WP_034164688.1site-specific tyrosine recombinase XerD-
MQ086_RS16520 (MQ086_16495)3544689..3545201+513WP_034164689.1flavodoxin FldB-
MQ086_RS16525 (MQ086_16500)3545226..3545642-417WP_034164690.1protein YgfXToxin
MQ086_RS16530 (MQ086_16505)3545623..3545889-267WP_012849755.1FAD assembly factor SdhEAntitoxin
MQ086_RS16535 (MQ086_16510)3546238..3547236+999WP_034164692.1tRNA-modifying protein YgfZ-
MQ086_RS16540 (MQ086_16515)3547278..3548102-825WP_034164693.1shikimate 5-dehydrogenase-
MQ086_RS16545 (MQ086_16520)3548259..3549131-873WP_034164695.1nucleoside-specific channel-forming protein Tsx-
MQ086_RS16550 (MQ086_16525)3549740..3550390+651WP_034164746.1hemolysin III family protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-131)

Antitoxin

(7-79)


Sequences


Toxin        


Download         Length: 139 a.a.        Molecular weight: 16229.03 Da        Isoelectric Point: 11.6049

>T239565 WP_034164690.1 NZ_CP094313:c3545642-3545226 [Edwardsiella anguillarum]
VVLWRCNVHVSWRTQVMFLLGHGALVLAILLAPWPENYSAFWLVLLVAVIFECIRSQRRIARNRGELQLLTPQVWHWQLR
EWRLARRPWVSDLGALLILQSTHGVPCRRRLWLAADSMSREEWGQLRRALLDTGDDRA

Download         Length: 417 bp

>T239565 NZ_LR898876:2038-2319 [Escherichia coli]
ATGATGGAGATATTCTGGACCATACTGGCCAGCCAGGACAGGAAGCGCATTCGTGAGTATATTGCGGAGCAGAACCTGAT
GGCTGCCATTGAACTGGACGAACGGATTGGTTATTCAGCCAGCAGCCTGGCCGGGCAGCCGTATAAAGGCCGCAACGGTC
GTGTGGAAGGTACCCGGGAACTGGTTATTCACCCGCATTTTGTTCTGGTTTATGAGGTCGACAGCCAGTGGGGAAAAGTG
TATATCCTGCGAGTATTGCATACTGCACAGAAGTGGCCATAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10318.90 Da        Isoelectric Point: 5.6951

>AT239565 WP_012849755.1 NZ_CP094313:c3545889-3545623 [Edwardsiella anguillarum]
MDINNKARVHWACRRGMRELDIAIMPFFEHEYDALNDADKQTFVRLLACDDPELFKWLMNQGKPDDADLARMITLIQTRN
KERGPLAL

Download         Length: 267 bp

>AT239565 NZ_LR898876:1772-2041 [Escherichia coli]
ATGGCACAGGTTAATATGAGTTTAAGAATCGACGCTGAACTGAAGGATGCTTTTATGGCCGCTGCAAAAAGCATGGACCG
TAATGGCTCTCAGTTAATTCGGGATTTTATGCGCCAGACCGTTGAACGGCAGCATAATACTTGGTTCCGTGACCAGGTTG
CGGCAGGACGTCAGCAACTCGAACGCGGCGATGTGCTTCCCCATGATATGGTCGAATCCTCCGCTACTGCATGGCGGGAT
GAAATAAGCAGGAAGGTCGCCGGTAAATGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
AlphaFold DBA0A034T2Q8

References