Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 28883..29508 Replicon plasmid unnamed4
Accession NZ_CP094305
Organism Edwardsiella anguillarum strain R18-08

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag MQ088_RS19975 Protein ID WP_098142458.1
Coordinates 28883..29281 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag MQ088_RS19980 Protein ID WP_098142459.1
Coordinates 29281..29508 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MQ088_RS19965 (MQ088_19940) 26017..26514 + 498 WP_283292378.1 hypothetical protein -
MQ088_RS19970 (MQ088_19945) 26601..28805 + 2205 WP_283292376.1 type IV conjugative transfer system coupling protein TraD -
MQ088_RS19975 (MQ088_19950) 28883..29281 - 399 WP_098142458.1 tRNA(fMet)-specific endonuclease VapC Toxin
MQ088_RS19980 (MQ088_19955) 29281..29508 - 228 WP_098142459.1 toxin-antitoxin system antitoxin VapB Antitoxin

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - papC / papD 1..91496 91496


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-125)

Antitoxin

SpoVT-AbrB domain

(7-53)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14835.08 Da        Isoelectric Point: 7.9270

>T239513 WP_098142458.1 NZ_CP094305:c29281-28883 [Edwardsiella anguillarum]
MLKYMLDTNICIFTLKNRPAQVRDKFNLHHNQMCISSITLMELIYGAEKSQSPEHNLAVIEGFIARLTVLNYDAPAAAHS
GQLRAEQARLGQPIGPYDQMIAGHARSQGLILVTNNTREFARVSGLRIEDWV

Download         Length: 399 bp

>T239513 NZ_LR898868:190263-190370 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8384.40 Da        Isoelectric Point: 4.7405

>AT239513 WP_098142459.1 NZ_CP094305:c29508-29281 [Edwardsiella anguillarum]
METTVFLSNRSQAVRLPKAVALPSDVKRVDIVAVGRTRIITPAGESWDSWFEGEGVSTDFMASREQPKGQEREDF

Download         Length: 228 bp

>AT239513 NZ_LR898868:c190215-190149 [Escherichia coli]
GGTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References