Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2028939..2029084 Replicon chromosome
Accession NZ_CP094237
Organism Klebsiella pneumoniae strain K41

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2028975..2029077 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2028939..2029084 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MQE26_RS09760 (MQE26_09760) 2024069..2026129 + 2061 WP_047694778.1 oligopeptidase B -
MQE26_RS09765 (MQE26_09765) 2026133..2026792 - 660 WP_002911407.1 exodeoxyribonuclease X -
MQE26_RS09770 (MQE26_09770) 2026871..2027101 - 231 WP_002911406.1 DNA polymerase III subunit theta -
MQE26_RS09775 (MQE26_09775) 2027214..2027588 + 375 WP_023285314.1 CopC domain-containing protein YobA -
MQE26_RS09780 (MQE26_09780) 2027592..2028461 + 870 WP_023285313.1 copper homeostasis membrane protein CopD -
MQE26_RS09785 (MQE26_09785) 2028478..2028816 + 339 WP_002911404.1 YebY family protein -
- 2028939..2029084 - 146 - - Antitoxin
- 2028975..2029077 + 103 - - Toxin
MQE26_RS09790 (MQE26_09790) 2029452..2029595 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
MQE26_RS09795 (MQE26_09795) 2029700..2030668 - 969 WP_004151446.1 VirK/YbjX family protein -
MQE26_RS09800 (MQE26_09800) 2030825..2031478 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
MQE26_RS09805 (MQE26_09805) 2031475..2031666 - 192 WP_002911395.1 YebW family protein -
MQE26_RS09810 (MQE26_09810) 2031764..2032003 - 240 WP_002911393.1 YebV family protein -
MQE26_RS09815 (MQE26_09815) 2032119..2033552 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T239350 NZ_CP094237:2028975-2029077 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT239350 NZ_CP094237:c2029084-2028939 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References