Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4137896..4138041 Replicon chromosome
Accession NZ_CP094227
Organism Klebsiella pneumoniae strain Bio3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4137903..4138005 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4137896..4138041 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MOO48_RS19695 4133427..4134860 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
MOO48_RS19700 4134976..4135215 + 240 WP_002911393.1 YebV family protein -
MOO48_RS19705 4135313..4135504 + 192 WP_002911395.1 YebW family protein -
MOO48_RS19710 4135501..4136154 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
MOO48_RS19715 4136311..4137279 + 969 WP_004151446.1 VirK/YbjX family protein -
MOO48_RS19720 4137384..4137527 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4137896..4138041 + 146 - - Antitoxin
- 4137903..4138005 - 103 - - Toxin
MOO48_RS19725 4138164..4138502 - 339 WP_002911404.1 YebY family protein -
MOO48_RS19730 4138519..4139388 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
MOO48_RS19735 4139392..4139766 - 375 WP_004151448.1 CopC domain-containing protein YobA -
MOO48_RS19740 4139879..4140109 + 231 WP_002911406.1 DNA polymerase III subunit theta -
MOO48_RS19745 4140188..4140847 + 660 WP_043906809.1 exodeoxyribonuclease X -
MOO48_RS19750 4140851..4142911 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T239318 NZ_CP094227:c4138005-4137903 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT239318 NZ_CP094227:4137896-4138041 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References