Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 581337..581961 Replicon chromosome
Accession NZ_CP094164
Organism Helicobacter pylori strain Hpfe0012

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MPG84_RS02795 Protein ID WP_245059866.1
Coordinates 581695..581961 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MPG84_RS02790 Protein ID WP_245059864.1
Coordinates 581337..581714 (+) Length 126 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MPG84_RS02765 (MPG84_02765) 576438..577550 + 1113 WP_245059852.1 hydrogenase formation protein HypD -
MPG84_RS02770 (MPG84_02770) 577501..578151 - 651 Protein_527 helicase DnaB modulator -
MPG84_RS02785 (MPG84_02785) 578535..580769 + 2235 WP_245059862.1 Hop family adhesin BabA -
MPG84_RS02790 (MPG84_02790) 581337..581714 + 378 WP_245059864.1 hypothetical protein Antitoxin
MPG84_RS02795 (MPG84_02795) 581695..581961 + 267 WP_245059866.1 type II toxin-antitoxin system YafQ family toxin Toxin
MPG84_RS02800 (MPG84_02800) 582067..582591 - 525 WP_001120213.1 acyl-CoA thioesterase -
MPG84_RS02805 (MPG84_02805) 582731..583573 + 843 WP_245059868.1 SDR family oxidoreductase -
MPG84_RS02810 (MPG84_02810) 583566..584546 + 981 WP_000921438.1 iron ABC transporter permease -
MPG84_RS02815 (MPG84_02815) 584546..585313 + 768 WP_000242366.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10315.14 Da        Isoelectric Point: 9.0170

>T239299 WP_245059866.1 NZ_CP094164:581695-581961 [Helicobacter pylori]
VLKLNLKKSFQKDFDKLLLNGFDDSVLNKVILSLRKKEPLDPQFQDHALKGNWKPFRECHIKPDILLVYLVKDDELILVR
LGSHSELF

Download         Length: 267 bp

>T239299 NZ_LR890666:183603-183908 [Klebsiella pneumoniae]
ATGCAGTTTAAGGTTTATGCCTATAAAAGAGAGAGCCGCTATCGTCTGTTCGTGGATGTGCAGAGTGACATCATCGATAC
CCCCGGGCGACGGATGGTGATCCCGCTGGCCAGCGCCCGGCTGCTGTCGGATAAAGTTTCCCGTGAACTCTATCCGGTGG
TGCACATCGGGGACGACAGCTACCGCCTGATGACCACGGACATGGCCAGCGTCACGGCCTCCGTCACCGGGGAGGAAGTG
GCCGATCTCAGCCACCGGGAAAATGACATCAAAAATGCGATAAACCTGATGTTCTGGGGAATTTGA

Antitoxin


Download         Length: 126 a.a.        Molecular weight: 14695.64 Da        Isoelectric Point: 5.3605

>AT239299 WP_245059864.1 NZ_CP094164:581337-581714 [Helicobacter pylori]
MPNSPTKKDCTQYSEKQLFNLINQLEQKIKKMQNDRVSFKEKMAKELEKRDQNFKDKIDALNELLQKISQAFDDKRDCCL
GYEIPNLETQQAMRDALNKETDLIVENFSSYSDERKRALGVETQP

Download         Length: 378 bp

>AT239299 NZ_LR890666:183383-183601 [Klebsiella pneumoniae]
ATGAAGCAGCGCATCACTGTCACCATAGACAGCGACAGTTATCAGTTACTGAAATCCGCAGACGTCAATATCTCCGCCCT
GGTGAACAGGGCCATGCAGAATGAGGCCCGTCGTCTGCGTGCCGAACGCTGGCAGGCTGAAAATCAGGAAGGGATGGCCG
AGGTTGCCCGCTTTATTGATATGAACGGTTCATTCGCCGACGAAAACAGGGACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References