Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 576329..576899 Replicon chromosome
Accession NZ_CP094161
Organism Helicobacter pylori strain Hpfe0015

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MPG04_RS02810 Protein ID WP_180413727.1
Coordinates 576627..576899 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MPG04_RS02805 Protein ID WP_050835443.1
Coordinates 576329..576640 (+) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MPG04_RS02780 (MPG04_02780) 571543..572655 + 1113 WP_245044765.1 hydrogenase formation protein HypD -
MPG04_RS02785 (MPG04_02785) 572606..573127 - 522 WP_245044767.1 hypothetical protein -
MPG04_RS02800 (MPG04_02800) 573634..575868 + 2235 WP_245044769.1 Hop family adhesin BabA -
MPG04_RS02805 (MPG04_02805) 576329..576640 + 312 WP_050835443.1 type II toxin-antitoxin system antitoxin Antitoxin
MPG04_RS02810 (MPG04_02810) 576627..576899 + 273 WP_180413727.1 type II toxin-antitoxin system YafQ family toxin Toxin
MPG04_RS02815 (MPG04_02815) 577005..577529 - 525 WP_064433216.1 acyl-CoA thioesterase -
MPG04_RS02820 (MPG04_02820) 577670..578512 + 843 WP_245044771.1 SDR family oxidoreductase -
MPG04_RS02825 (MPG04_02825) 578505..579485 + 981 WP_000921438.1 iron ABC transporter permease -
MPG04_RS02830 (MPG04_02830) 579485..580252 + 768 WP_245044774.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10626.64 Da        Isoelectric Point: 9.7265

>T239297 WP_180413727.1 NZ_CP094161:576627-576899 [Helicobacter pylori]
MLMIETNKKFDKDLKILVKNGFDLKLLYKVVENLAKEQPLDPKYKDHPLKGALKDFRECHLKPDLLLVYQIKKQENTLFL
VRLGSHSELF

Download         Length: 273 bp

>T239297 NZ_LR890666:162599-163126 [Klebsiella pneumoniae]
GTGATGCAAGAGCTGGCGATAGAGATGATCAACGACGAATTTGACTATGACATAGGCGAATTCGATTGTGGAGAAGAAAC
CTTAAATACATTTTTGAAAGACCATCTCAAGCGGCAGCATGATGGGCAAATTTTAAAAGGTTATGTATTAGTAACCAAAG
AACAGAAGCCTAAGCTGTTAGGCTATTACACATTATCCGGGAGCTGTTTCGAGAGAAAAATGCTCCCGTCAAAAACACAG
CAAAGAAAAATCCCTTATCAGAATGCGCCAAGCATTACTTTGGGACGCTTGGCTATTGACAAATCAATTCAAGGTCAGGG
ATGGGGTGAATTGCTAGTAACTCACGCAATGAATGTCGTCTGGGATGCATCTAAGGCCGTAGGGATATATGGTCTCTTCG
TGGAAGCTCTGAACGATAAAGCTAAGCGCTTCTATACCAGATTAGATTTCATACAGCTCGTTGGTGAGAATAGTAATCTG
CTATTTTACCCGACAAAATCTATTGAAAAAATCTTTACCGAAGAGTAA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 12318.17 Da        Isoelectric Point: 10.2819

>AT239297 WP_050835443.1 NZ_CP094161:576329-576640 [Helicobacter pylori]
MPNSPTKKDYTRYSEKQLFNFLNSIKTKQKRALEKLKEIQAQKQRIKKALQFKALHLTENGYTIEEEREILARAKDTKNH
LCFKSVEDFKKHCENLRFKNADD

Download         Length: 312 bp

>AT239297 NZ_LR890666:162322-162591 [Klebsiella pneumoniae]
ATGTCCGCACTGAGAAAGCAGCGCATAGATCTAAGATTAACTGATGACGACAAAAGCTTAATCGAAGAAGCCGCGGCAAT
GTCAAACCAGACTATTACACAGTTTGTAGTTGCCAGTGCCTCAGAACGTGCAGCGGAAGTGATTGAACAACATCGCAGAA
TGGTTCTAAACGAGGAGTCTTGGAACCTTGTCATGGATGCGATCGCAAACCCTGCTGCGCCGAATGAGCGGCTGAAGCGA
GCAGCGAAGCGTCTACAAAAAATGAGGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References