239286

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 578817..579441 Replicon chromosome
Accession NZ_CP094150
Organism Helicobacter pylori strain Hpfe022

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MPG09_RS02795 Protein ID WP_245027635.1
Coordinates 579175..579441 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MPG09_RS02790 Protein ID WP_245027634.1
Coordinates 578817..579188 (+) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MPG09_RS02765 (MPG09_02765) 573947..575059 + 1113 WP_245027631.1 hydrogenase formation protein HypD -
MPG09_RS02770 (MPG09_02770) 575010..575531 - 522 WP_245027632.1 hypothetical protein -
MPG09_RS02785 (MPG09_02785) 576056..578287 + 2232 WP_245027633.1 Hop family adhesin BabA -
MPG09_RS02790 (MPG09_02790) 578817..579188 + 372 WP_245027634.1 hypothetical protein Antitoxin
MPG09_RS02795 (MPG09_02795) 579175..579441 + 267 WP_245027635.1 type II toxin-antitoxin system YafQ family toxin Toxin
MPG09_RS02800 (MPG09_02800) 579548..580072 - 525 WP_001135602.1 acyl-CoA thioesterase -
MPG09_RS02805 (MPG09_02805) 580212..581060 + 849 WP_245027636.1 SDR family oxidoreductase -
MPG09_RS02810 (MPG09_02810) 581053..582033 + 981 WP_000921452.1 iron ABC transporter permease -
MPG09_RS02815 (MPG09_02815) 582033..582800 + 768 WP_000242365.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10449.47 Da        Isoelectric Point: 10.1823

>T239286 WP_245027635.1 NZ_CP094150:579175-579441 [Helicobacter pylori]
MLKIKHHILYKKDFKKLVKNGFDDSVLNKVILSLRKKEPLDPQFQDHALKGKWKPFRECHLKPDLLLVYLVKDDELILVR
LGSHSELF

Download         Length: 267 bp

>T239286 NZ_LR890665:336285-336653 [Klebsiella pneumoniae]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCGGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GCCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACCCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCAGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCAGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGTTTGCGTGGATGA

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 14455.46 Da        Isoelectric Point: 9.0537

>AT239286 WP_245027634.1 NZ_CP094150:578817-579188 [Helicobacter pylori]
MPNTTAKKDYTQYSEKQLVNLIHQLERKIKKMQNDRVSFKERMAKELEKRDQNFKDKIDALNKLLQKISQAFDDKRDCCL
GRKIPNIQTQQAMRDALNGENLETIEDLSAWANEVKKEVNAEN

Download         Length: 372 bp

>AT239286 NZ_LR890665:336067-336288 [Klebsiella pneumoniae]
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTACCTGTGAC
CATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGGCGGCCAGAATGGATG
ATGAGTTCGCGGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References