239264

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 582582..583206 Replicon chromosome
Accession NZ_CP094136
Organism Helicobacter pylori strain Hpfe039

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MPF95_RS02835 Protein ID WP_180499586.1
Coordinates 582940..583206 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MPF95_RS02830 Protein ID WP_245067502.1
Coordinates 582582..582959 (+) Length 126 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MPF95_RS02805 (MPF95_02805) 577749..578861 + 1113 WP_245067488.1 hydrogenase formation protein HypD -
MPF95_RS02810 (MPF95_02810) 578812..579426 - 615 WP_245067490.1 helicase DnaB modulator -
MPF95_RS02825 (MPF95_02825) 579837..582071 + 2235 WP_245067500.1 Hop family adhesin BabA -
MPF95_RS02830 (MPF95_02830) 582582..582959 + 378 WP_245067502.1 hypothetical protein Antitoxin
MPF95_RS02835 (MPF95_02835) 582940..583206 + 267 WP_180499586.1 type II toxin-antitoxin system YafQ family toxin Toxin
MPF95_RS02840 (MPF95_02840) 583312..583836 - 525 WP_001135602.1 acyl-CoA thioesterase -
MPF95_RS02845 (MPF95_02845) 583979..584821 + 843 WP_245067504.1 SDR family oxidoreductase -
MPF95_RS02850 (MPF95_02850) 584814..585794 + 981 WP_000921481.1 iron ABC transporter permease -
MPF95_RS02855 (MPF95_02855) 585794..586561 + 768 WP_000242365.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10289.14 Da        Isoelectric Point: 9.6292

>T239264 WP_180499586.1 NZ_CP094136:582940-583206 [Helicobacter pylori]
VLKLNLKKSFQKDFDKLLLNGFDDSVLNKVILSLRKKEPLDPQFKDHALKGNWKPFRECHIKADILLVYLVKDDELILVR
LGSHSELF

Download         Length: 267 bp

>T239264 NZ_LR890652:40115-40531 [Escherichia coli]
GTGAACAAGATCTATATGCTCGACACGAACATCTGCTCGTTCATCATGCGCGAGCAACCTGAAGCATTGCTTAAGCACCT
GGAGCAGTCGGTGCTGCGCGGTCACCGTATCGTGGTCTCGGCCATCACCTACTCCGAGATGCGCTTCGGTGCCACCGGTC
CGAAGGCCTCGCCACGCCACGTGCAACTGGTTGACGCGTTCTGTGAGAGGCTCGATGCCGTCCTGCCGTGGGACCGCGCC
GCGGTGGATGCGACCACGGAGATTAAGGTGGCACTGCGTCTCGCCGGCACGCCGATCGGTCCGAACGACACGGCGATAGC
CGGACACGCCATCGCTGCCTGTGCCATTCTGGTGACGAATAATGTGAGAGAGTTTGAGCGGGTACCGGGTCTTGTGCTGG
AAGACTGGGTAAGATAA

Antitoxin


Download         Length: 126 a.a.        Molecular weight: 14676.58 Da        Isoelectric Point: 7.8152

>AT239264 WP_245067502.1 NZ_CP094136:582582-582959 [Helicobacter pylori]
MPNTTAKKDYTQYSEKQLFNLINQLEQKIKKMQNDRASFKEKMAKELEKRDQNFKDKIDALNKLLQKISQAFDDKRDCCL
GHETPNLETQQAMRDALNKETDLIVENFSSYSDERKRALGVETQP

Download         Length: 378 bp

>AT239264 NZ_LR890652:39888-40118 [Escherichia coli]
ATGAGAACCGTATCCATTTTTAAAAATGGCAACAACCGTGCTATCCGCCTTCCACGCGATCTGGATTTTGAGGGGGTGAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATCATTCTGCGCCCCGTCCGGCCGACCTGGGGCTCATTCCTGGAGCTAG
AAAAGGCCGATCCGGACTTTATGACGGAGCGCGAGGACGTTGTCAGCGACGAAGGACGAGTTAACCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References