Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 581533..582157 Replicon chromosome
Accession NZ_CP094131
Organism Helicobacter pylori strain Hpfe052

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MPG30_RS02795 Protein ID WP_180499586.1
Coordinates 581891..582157 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MPG30_RS02790 Protein ID WP_245048220.1
Coordinates 581533..581910 (+) Length 126 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MPG30_RS02765 (MPG30_02765) 576760..577872 + 1113 WP_245048218.1 hydrogenase formation protein HypD -
MPG30_RS02770 (MPG30_02770) 577823..578472 - 650 Protein_527 helicase DnaB modulator -
MPG30_RS02785 (MPG30_02785) 578843..581068 + 2226 WP_245048219.1 Hop family adhesin BabA -
MPG30_RS02790 (MPG30_02790) 581533..581910 + 378 WP_245048220.1 hypothetical protein Antitoxin
MPG30_RS02795 (MPG30_02795) 581891..582157 + 267 WP_180499586.1 type II toxin-antitoxin system YafQ family toxin Toxin
MPG30_RS02800 (MPG30_02800) 582262..582786 - 525 WP_245048221.1 acyl-CoA thioesterase -
MPG30_RS02805 (MPG30_02805) 582927..583769 + 843 WP_245048222.1 SDR family oxidoreductase -
MPG30_RS02810 (MPG30_02810) 583762..584742 + 981 WP_000921482.1 iron ABC transporter permease -
MPG30_RS02815 (MPG30_02815) 584742..585509 + 768 WP_220913229.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10289.14 Da        Isoelectric Point: 9.6292

>T239257 WP_180499586.1 NZ_CP094131:581891-582157 [Helicobacter pylori]
VLKLNLKKSFQKDFDKLLLNGFDDSVLNKVILSLRKKEPLDPQFKDHALKGNWKPFRECHIKADILLVYLVKDDELILVR
LGSHSELF

Download         Length: 267 bp

>T239257 NZ_LR890651:3677941-3678483 [Escherichia coli]
ATGGTCGACAAGCATGAAGAGATTACTCTGCCCATAGTCCTCTCCTGTAATTATCAGTCTGATATTACTTATCCTGGGCA
AAAACAGTTTGATTGCGGTAACCCTGTTATCGATAAATTTGTACGCGCATCGCTAAAGAAAAGTGTGCGTAATAGCGACT
GTGCGGCTAAAGCACTTATTGACAGACAAAGTGGTGAACTGATCGGCATCTGTACTTTTACGGCATATTCGCTGGAAAAA
CAACGCGTTTCTGGCGTCCTTCAGGGTTCACAACCTTCAGAAATTGGTGTTGTCAGATTAGTCATGTTGGGGGTAGCACG
GAAGTATCAAAAGCGGGGCTTTGGTCAGGACCTACTATGTGATTTTTTTGAACATGTAAAAATAATTCACCAGGCATTAC
CAATTAAAGGGGTTTATCTTGATGCTGACCCTGCCGCCATTAATTTTTATGCTCGTCTCGGCTTTGTTCAGCTTTCAGCG
ACACCAAATGCTTTTGGTGCTGTACCTATGTTTTTGGCGATTCAGCATATTCTCGCGGCTTAG

Antitoxin


Download         Length: 126 a.a.        Molecular weight: 14782.57 Da        Isoelectric Point: 5.0647

>AT239257 WP_245048220.1 NZ_CP094131:581533-581910 [Helicobacter pylori]
MPNSPTKKDYTQYSEKQLFNLINQLEQKIKKMQNDRASFKEKMAKELEKRDQNFKDKIDALNELLQKISQAFDDKRDCCF
DHETPNLETQQAMRDALNKETDLIVEDFSSYSDERKRALGVETQP

Download         Length: 378 bp

>AT239257 NZ_LR890651:3677646-3677957 [Escherichia coli]
ATGCCTGGAAAAACAGCCACTCTACCCGATGTCGATAAAACGCTGAAAAATGCGCGGGTCGAACTCAAAACTAGTCCCGA
CGCCAAAAACAAACTTCGTGAAGCTGCGCAAGCCGTTGGGGTAGATTTAAGCGCTTTTATTTTGAGCGCTGCTATGGAAC
GCGCCGAAAGTGTGCTTGATAACCAACGTCGCCGTGAGCTTTCGAATCAAAGCTGGGAACTGATGAACCAACTCATCGCT
GAACCTGCTCAACCGACGCTCGCCCTCAAGGCGTTAATGAAAAGGAAAAACAGCGATGGTCGACAAGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References