239255

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 576530..577100 Replicon chromosome
Accession NZ_CP094129
Organism Helicobacter pylori strain Hpfe054

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MPG85_RS02825 Protein ID WP_180475647.1
Coordinates 576828..577100 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0M0MSJ1
Locus tag MPG85_RS02820 Protein ID WP_001133857.1
Coordinates 576530..576841 (+) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MPG85_RS02795 (MPG85_02795) 571592..572704 + 1113 WP_245051256.1 hydrogenase formation protein HypD -
MPG85_RS02800 (MPG85_02800) 572655..573305 - 651 Protein_533 helicase DnaB modulator -
MPG85_RS02815 (MPG85_02815) 573693..575927 + 2235 WP_245051258.1 Hop family adhesin BabA -
MPG85_RS02820 (MPG85_02820) 576530..576841 + 312 WP_001133857.1 type II toxin-antitoxin system antitoxin Antitoxin
MPG85_RS02825 (MPG85_02825) 576828..577100 + 273 WP_180475647.1 type II toxin-antitoxin system YafQ family toxin Toxin
MPG85_RS02830 (MPG85_02830) 577208..577732 - 525 WP_001135615.1 hotdog domain-containing protein -
MPG85_RS02835 (MPG85_02835) 577872..578714 + 843 WP_245051260.1 SDR family oxidoreductase -
MPG85_RS02840 (MPG85_02840) 578707..579687 + 981 WP_140500224.1 iron ABC transporter permease -
MPG85_RS02845 (MPG85_02845) 579687..580454 + 768 WP_000242363.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10599.61 Da        Isoelectric Point: 9.7265

>T239255 WP_180475647.1 NZ_CP094129:576828-577100 [Helicobacter pylori]
MLMIETSKKFDKDLKILVKNGFDLKLLYKVVENLAKEQPLDPKYKDHPLKGALKDFRECHIKPDILLVYQIKKQENTLFL
VRLGSHSELF

Download         Length: 273 bp

>T239255 NZ_LR890651:2834165-2834272 [Escherichia coli]
ATGACGCTCGCGAAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 12331.16 Da        Isoelectric Point: 10.1678

>AT239255 WP_001133857.1 NZ_CP094129:576530-576841 [Helicobacter pylori]
MPNSPTKKDYTQYSEKQLFNFLNSIKTKQKRALEKLKEIQAQKQRIKKALQFKALHLTENGYTIEEEREILARAKDTKNH
LCFKNIEDFKKHCENLRFKNADD

Download         Length: 312 bp

>AT239255 NZ_LR890651:c2834112-2834051 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0M0MSJ1

References