Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 4114594..4115336 Replicon chromosome
Accession NC_012880
Organism Dickeya dadantii Ech703

Toxin (Protein)


Gene name ataT Uniprot ID C6C3X4
Locus tag DD703_RS17630 Protein ID WP_015855199.1
Coordinates 4114857..4115336 (+) Length 160 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID C6C3X3
Locus tag DD703_RS17625 Protein ID WP_015855198.1
Coordinates 4114594..4114866 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
- 4114594..4114866 + 273 - - Antitoxin

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 4111972..4126083 14111
- flank IS/Tn - - 4115930..4116967 1037


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(28-147)

Antitoxin

Vibrio phage ICP1, Orf50

(10-85)


Sequences

Toxin        


Download         Length: 160 a.a.        Molecular weight: 17538.30 Da        Isoelectric Point: 9.5367

>T23925 WP_015855199.1 NC_012880:4114857-4115336 [Dickeya paradisiaca Ech703]
VGITAPELLLPQHAVVDFHCSEPSLNEWLKRKALKNQTLGASRTFVVCEAGTQRVVGFYALASGSIQRQVAPGAFRRNMP
DPIPVLVLGRLAVDERYQRMGIGAGLLKDAVLRSRNVAQQVGNKALLVHALSDEAKAFYQYWGFVASEIQEHTLLLSLW

Download         Length: 480 bp

>T23925 NC_012880:4114857-4115336 [Dickeya paradisiaca Ech703]
GTGGGAATAACGGCACCTGAATTATTGCTGCCTCAACATGCGGTTGTGGATTTTCATTGTTCAGAGCCGTCATTGAATGA
ATGGCTGAAACGCAAGGCGTTAAAAAATCAGACGCTGGGCGCTTCACGCACCTTCGTGGTGTGTGAAGCCGGTACACAGC
GTGTGGTGGGGTTCTATGCCCTCGCGTCGGGTAGCATCCAGCGTCAGGTTGCACCGGGCGCATTCCGGCGCAATATGCCT
GACCCCATTCCTGTTCTGGTACTTGGCCGATTAGCCGTTGATGAACGTTATCAACGCATGGGGATCGGTGCCGGGCTTCT
GAAAGATGCGGTACTCCGCTCCCGCAATGTAGCGCAGCAGGTAGGCAACAAAGCGTTATTGGTACATGCGTTATCTGATG
AGGCAAAAGCGTTCTACCAATACTGGGGTTTTGTCGCGTCAGAAATACAGGAACACACCTTATTATTATCGTTATGGTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10388.91 Da        Isoelectric Point: 4.8779

>AT23925 WP_015855198.1 NC_012880:4114594-4114866 [Dickeya paradisiaca Ech703]
MRTETKEMPINIRAKASQRELIDVAAKLLSKSRTEFILDAACREAEDVLLDQRLFLVNDEQYDAFIKVLESPVTDNPRVN
ALLNRKSPWE

Download         Length: 273 bp

>AT23925 NC_012880:4114594-4114866 [Dickeya paradisiaca Ech703]
ATGCGAACAGAGACAAAAGAAATGCCGATTAATATTCGTGCTAAAGCATCACAGCGGGAGCTGATTGATGTCGCTGCTAA
ATTGCTGTCGAAATCAAGAACAGAGTTTATCCTTGATGCTGCCTGCCGTGAGGCTGAGGATGTGTTGTTGGATCAACGGC
TGTTTCTGGTCAATGATGAACAATATGATGCTTTCATTAAGGTGCTGGAATCACCTGTCACAGATAATCCGCGTGTGAAT
GCATTACTGAACAGGAAATCTCCGTGGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2K8QHE3

Antitoxin

Source ID Structure
AlphaFold DB C6C3X3

References