Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 578835..579453 Replicon chromosome
Accession NZ_CP094109
Organism Helicobacter pylori strain Hpfe072

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MPG41_RS02775 Protein ID WP_245068273.1
Coordinates 579193..579453 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MPG41_RS02770 Protein ID WP_245068271.1
Coordinates 578835..579206 (+) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MPG41_RS02745 (MPG41_02745) 573911..575023 + 1113 WP_245068265.1 hydrogenase formation protein HypD -
MPG41_RS02750 (MPG41_02750) 574974..575495 - 522 WP_245068267.1 hypothetical protein -
MPG41_RS02765 (MPG41_02765) 575996..578230 + 2235 WP_245068269.1 Hop family adhesin BabA -
MPG41_RS02770 (MPG41_02770) 578835..579206 + 372 WP_245068271.1 hypothetical protein Antitoxin
MPG41_RS02775 (MPG41_02775) 579193..579453 + 261 WP_245068273.1 type II toxin-antitoxin system YafQ family toxin Toxin
MPG41_RS02780 (MPG41_02780) 579557..580081 - 525 WP_057112890.1 acyl-CoA thioesterase -
MPG41_RS02785 (MPG41_02785) 580221..581063 + 843 WP_245068275.1 SDR family oxidoreductase -
MPG41_RS02790 (MPG41_02790) 581056..582036 + 981 WP_000921438.1 iron ABC transporter permease -
MPG41_RS02795 (MPG41_02795) 582036..582803 + 768 WP_245068277.1 ABC transporter ATP-binding protein -
MPG41_RS02800 (MPG41_02800) 582866..583992 + 1127 Protein_530 glycosyltransferase family 8 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10152.12 Da        Isoelectric Point: 10.2127

>T239236 WP_245068273.1 NZ_CP094109:579193-579453 [Helicobacter pylori]
MLKIKHHILYKKDFKKLIKNGFDDSVLNEVILRKKEPLSPQFQDHALKGKWKPFRECHIKADILLVYLVKGDELILVRLG
SHSELF

Download         Length: 261 bp

>T239236 NZ_LR890648:4032394-4032612 [Klebsiella pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACTTCTGTCTGGAAATTTATCCGCTAA

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 14430.34 Da        Isoelectric Point: 8.8435

>AT239236 WP_245068271.1 NZ_CP094109:578835-579206 [Helicobacter pylori]
MPNSSAKKDYTRYSEKQLFSLINQLEQKIKKMQNDRASFKEKMAKELEKRDQNFKDKIDALNKLLQKISQAFDDKRDCYL
GRKIPNLETQQAMRDALNGENLETIEDLSAWANEVKKEVNAEN

Download         Length: 372 bp

>AT239236 NZ_LR890648:4031993-4032367 [Klebsiella pneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References