Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 578197..578821 Replicon chromosome
Accession NZ_CP094093
Organism Helicobacter pylori strain Hpfe085

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MPF97_RS02800 Protein ID WP_245102971.1
Coordinates 578555..578821 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MPF97_RS02795 Protein ID WP_245102969.1
Coordinates 578197..578568 (+) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MPF97_RS02770 (MPF97_02770) 573325..574437 + 1113 WP_245102966.1 hydrogenase formation protein HypD -
MPF97_RS02775 (MPF97_02775) 574388..575030 - 643 Protein_528 helicase DnaB modulator -
MPF97_RS02790 (MPF97_02790) 575407..577641 + 2235 WP_245102967.1 Hop family adhesin BabA -
MPF97_RS02795 (MPF97_02795) 578197..578568 + 372 WP_245102969.1 hypothetical protein Antitoxin
MPF97_RS02800 (MPF97_02800) 578555..578821 + 267 WP_245102971.1 type II toxin-antitoxin system YafQ family toxin Toxin
MPF97_RS02805 (MPF97_02805) 578926..579450 - 525 WP_001135603.1 acyl-CoA thioesterase -
MPF97_RS02810 (MPF97_02810) 579590..580432 + 843 WP_245102973.1 SDR family oxidoreductase -
MPF97_RS02815 (MPF97_02815) 580425..581405 + 981 WP_000921458.1 iron chelate uptake ABC transporter family permease subunit -
MPF97_RS02820 (MPF97_02820) 581405..582172 + 768 WP_000242366.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10452.47 Da        Isoelectric Point: 10.2119

>T239219 WP_245102971.1 NZ_CP094093:578555-578821 [Helicobacter pylori]
MLKIKHHILYKKDFKKLIKNGFDDSVLNEVILTLRKKETLDPQFKDHALRGKWKPFRECHIKPDILLVYLVKGDELILVR
LGSHSELF

Download         Length: 267 bp

>T239219 NZ_LR890643:362096-362443 [Klebsiella pneumoniae]
ATGTGGGATGTAGAAACGACGGATACGTTTGATACCTGGTTCGAATTACAAAGTAGAGCTTTAAAAGAGGATATGTTGGC
CACGATGCTCATCCTGTCTGAGTTTGCTCCGCAGCTTGGGCGCCCGTATGTTGATACGGTGAAAGATTCAACGTTTCAGA
ATATGAAAGAACTGCGGGTTCAGCATCATGGGCTCCCCATCCGCGCCTTTTTTGCTTTTGATCCTCTGCGGAAAGCTATC
GTTTTATGTGCGGGCAATAAGGATGGCATGAATGAGAAACGTTTTTACAAAGAGATGATTACTCTGGCTGACAGAGAATT
CAGCCAACACCTGACTAAGGAGCGATAA

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 14380.34 Da        Isoelectric Point: 7.7809

>AT239219 WP_245102969.1 NZ_CP094093:578197-578568 [Helicobacter pylori]
MPNSPTKKDYTQYSEKQLFNLINQLEQKIKKMQNDRVSFKEKMAKELEKRDQNFKDKIDALNGLLQKISQAFDDKRDCCL
GRKIPNLETQQAMRDALKGENLETIEDLSAWANEVKKEVNAEN

Download         Length: 372 bp

>AT239219 NZ_LR890643:362443-362742 [Klebsiella pneumoniae]
ATGGCCACGCTAAAAGAACTCATGGCGAAACAGAGTCCTGATAGCCAGCAGCGTATTGCAGCGAAAGCGGCAGAGATACG
CCAGTCTGTCGCTTTAAACTTGCTTCGAGAAGAGTTGCAAATGTCGCAAACAGAGATGGCTGCGGCTATGGGGGTAAAGC
AGCCAACGATCGCTAAAATGGAACAGGCTGATAACGACCCTCGGCTTTCGACCCTAAAACGCTACATTGCGGCATGGGGG
GGAGAACTCAGTATAAATGTCACATTGCCGACTGGAAAAAAAGTCTCGTTTAATTTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References