Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 599503..600127 Replicon chromosome
Accession NZ_CP094087
Organism Helicobacter pylori strain Hpfe093

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MPG15_RS02910 Protein ID WP_245079808.1
Coordinates 599861..600127 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MPG15_RS02905 Protein ID WP_245079807.1
Coordinates 599503..599880 (+) Length 126 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MPG15_RS02880 (MPG15_02880) 594643..595755 + 1113 WP_245079805.1 hydrogenase formation protein HypD -
MPG15_RS02885 (MPG15_02885) 595706..596278 - 573 WP_245079974.1 helicase DnaB modulator -
MPG15_RS02900 (MPG15_02900) 596736..598970 + 2235 WP_245079806.1 Hop family adhesin BabA -
MPG15_RS02905 (MPG15_02905) 599503..599880 + 378 WP_245079807.1 hypothetical protein Antitoxin
MPG15_RS02910 (MPG15_02910) 599861..600127 + 267 WP_245079808.1 type II toxin-antitoxin system YafQ family toxin Toxin
MPG15_RS02915 (MPG15_02915) 600233..600757 - 525 WP_096481922.1 acyl-CoA thioesterase -
MPG15_RS02920 (MPG15_02920) 600898..601740 + 843 WP_245079810.1 SDR family oxidoreductase -
MPG15_RS02925 (MPG15_02925) 601733..602713 + 981 WP_000921438.1 iron ABC transporter permease -
MPG15_RS02930 (MPG15_02930) 602713..603480 + 768 WP_058060476.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10347.22 Da        Isoelectric Point: 9.6292

>T239213 WP_245079808.1 NZ_CP094087:599861-600127 [Helicobacter pylori]
VLKLNLKKSFQKDFDKLLLNGFNDSVLNEVILTLRKKEPLDPQFKDHALKGKWKPFRECHIKSDILLVYLVKDDELILLR
LGSHSELF

Download         Length: 267 bp

>T239213 NZ_LR890641:51970-52293 [Klebsiella pneumoniae]
ATGAACTATCTGGAGTTTGTTGAAACCAGCGCTTTCAGTGGACTGCGTAAGGAACTCATGGATGATGATGAATTCCGCGA
ACTGCAGACCTATTTACTGGAAGCCCATGATCGGGGTGACACCATCAGTCATACCGGTGGATGCAGGAAGATTCGCTGGG
GTCGCCCGGGGATGGGTAAGCGAGGTGGCGTCAGGGTGATTTACTACGTTCGTCTTGCCAGCGGCAGACTGTATCTGCTG
CTGATATACCCGAAGAATGCGAAAGATGAGCTCAGCGAGAAAGAAAAAGCCGTTATGAAGGCATTAACACAGCAGCTGAA
GTAA

Antitoxin


Download         Length: 126 a.a.        Molecular weight: 14727.71 Da        Isoelectric Point: 7.7731

>AT239213 WP_245079807.1 NZ_CP094087:599503-599880 [Helicobacter pylori]
MPNSPTKKDYTRYSEKQLFNLINQLEQKIKKMQNDRASFKEKMAKELEKRDQNFKDKIDALNKLLQKISQAFDDKRDCCL
GYEIPNLETQQAMRDALNKETDLIVEDFSSYSDERKKALGVETQP

Download         Length: 378 bp

>AT239213 NZ_LR890641:52342-52644 [Klebsiella pneumoniae]
ATGGAAAAGAAACTTTTTGATGCCCTGATCAGCAGCATGGAGGAAATGGTGGCCATTGAAAATGGCCAGATCCAGCCCGC
TGCAGAACAGGTTCACCGCCATACACTGCCGGATGTGAAAGCCATTCGTAAACATGCCGGCATGAAACAGGCTGAATTTG
CAGAAGTGGTGGGGGCCAGCGTTGACCTTGTTCGCAGCTGGGAACAGCAACGGCGTGTTCCGTCGGGTATTGCGCTGAAA
ATGCTCTGCCTCATCGAGCGTGAGCCTGCACTGATTAATACGTTGCGTGGTATTCACGTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References