Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/YafQ(toxin) |
Location | 1008330..1008982 | Replicon | chromosome |
Accession | NZ_CP094085 | ||
Organism | Helicobacter pylori strain Hpfe095 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | MPG64_RS04800 | Protein ID | WP_245075792.1 |
Coordinates | 1008722..1008982 (-) | Length | 87 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | MPG64_RS04795 | Protein ID | WP_245077106.1 |
Coordinates | 1008330..1008641 (-) | Length | 104 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
MPG64_RS04770 (MPG64_04770) | 1004719..1005486 | - | 768 | WP_220884645.1 | ABC transporter ATP-binding protein | - |
MPG64_RS04775 (MPG64_04775) | 1005486..1006466 | - | 981 | WP_000921482.1 | iron ABC transporter permease | - |
MPG64_RS04780 (MPG64_04780) | 1006459..1007301 | - | 843 | WP_180632348.1 | SDR family oxidoreductase | - |
MPG64_RS04785 (MPG64_04785) | 1007442..1007966 | + | 525 | WP_001135603.1 | acyl-CoA thioesterase | - |
MPG64_RS04790 (MPG64_04790) | 1008071..1008343 | - | 273 | WP_140477329.1 | type II toxin-antitoxin system mRNA interferase toxin, HP0892 family | - |
MPG64_RS04795 (MPG64_04795) | 1008330..1008641 | - | 312 | WP_245077106.1 | type II toxin-antitoxin system antitoxin | Antitoxin |
MPG64_RS04800 (MPG64_04800) | 1008722..1008982 | - | 261 | WP_245075792.1 | type II toxin-antitoxin system YafQ family toxin | Toxin |
MPG64_RS04805 (MPG64_04805) | 1008963..1009339 | - | 377 | Protein_948 | hypothetical protein | - |
MPG64_RS04810 (MPG64_04810) | 1009621..1011852 | - | 2232 | WP_245075794.1 | Hop family adhesin BabA | - |
MPG64_RS04825 (MPG64_04825) | 1012219..1012862 | + | 644 | Protein_950 | helicase DnaB modulator | - |
MPG64_RS04830 (MPG64_04830) | 1012813..1013925 | - | 1113 | WP_245075796.1 | hydrogenase formation protein HypD | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 87 a.a. Molecular weight: 10147.93 Da Isoelectric Point: 8.0602
>T239212 WP_245075792.1 NZ_CP094085:c1008982-1008722 [Helicobacter pylori]
VLKLNLKKSFQKDFDKLLLNGFDDSVLNEVILRKKEPLDPQFKDHALKGKWKPFRECHIKTDILLVYLVQDDELILLRLG
SHSELF
VLKLNLKKSFQKDFDKLLLNGFDDSVLNEVILRKKEPLDPQFKDHALKGKWKPFRECHIKTDILLVYLVQDDELILLRLG
SHSELF
Download Length: 261 bp
>T239212 NZ_LR890640:4597677-4598087 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAAATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAAATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA
Antitoxin
Download Length: 104 a.a. Molecular weight: 12323.09 Da Isoelectric Point: 9.9013
>AT239212 WP_245077106.1 NZ_CP094085:c1008641-1008330 [Helicobacter pylori]
MPNTTTEKDYTQYSEKQLFNFLNSIKTKQKRALEKLKEIQAQKQRIKKALQFKALHLTENGYTIEEEREILARAKDTKNH
LCFKSIEDFKKHCENLRFKNADD
MPNTTTEKDYTQYSEKQLFNFLNSIKTKQKRALEKLKEIQAQKQRIKKALQFKALHLTENGYTIEEEREILARAKDTKNH
LCFKSIEDFKKHCENLRFKNADD
Download Length: 312 bp
>AT239212 NZ_LR890640:4597430-4597696 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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