Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 1008071..1008641 Replicon chromosome
Accession NZ_CP094085
Organism Helicobacter pylori strain Hpfe095

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MPG64_RS04790 Protein ID WP_140477329.1
Coordinates 1008071..1008343 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MPG64_RS04795 Protein ID WP_245077106.1
Coordinates 1008330..1008641 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MPG64_RS04770 (MPG64_04770) 1004719..1005486 - 768 WP_220884645.1 ABC transporter ATP-binding protein -
MPG64_RS04775 (MPG64_04775) 1005486..1006466 - 981 WP_000921482.1 iron ABC transporter permease -
MPG64_RS04780 (MPG64_04780) 1006459..1007301 - 843 WP_180632348.1 SDR family oxidoreductase -
MPG64_RS04785 (MPG64_04785) 1007442..1007966 + 525 WP_001135603.1 acyl-CoA thioesterase -
MPG64_RS04790 (MPG64_04790) 1008071..1008343 - 273 WP_140477329.1 type II toxin-antitoxin system mRNA interferase toxin, HP0892 family Toxin
MPG64_RS04795 (MPG64_04795) 1008330..1008641 - 312 WP_245077106.1 type II toxin-antitoxin system antitoxin Antitoxin
MPG64_RS04800 (MPG64_04800) 1008722..1008982 - 261 WP_245075792.1 type II toxin-antitoxin system YafQ family toxin -
MPG64_RS04805 (MPG64_04805) 1008963..1009339 - 377 Protein_948 hypothetical protein -
MPG64_RS04810 (MPG64_04810) 1009621..1011852 - 2232 WP_245075794.1 Hop family adhesin BabA -
MPG64_RS04825 (MPG64_04825) 1012219..1012862 + 644 Protein_950 helicase DnaB modulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10585.63 Da        Isoelectric Point: 9.9378

>T239211 WP_140477329.1 NZ_CP094085:c1008343-1008071 [Helicobacter pylori]
MLMIETSKKFDKDLKILVKNGFDLKLLYKVVENLAKEQPLAPKYKDHPLKGTLKDFRECHLKPDLLLVYQIKKQENTLFL
VRLGSHSELF

Download         Length: 273 bp

>T239211 NZ_LR890640:4532074-4532559 [Klebsiella pneumoniae]
ATGATCTTGGCACCAGAACCGCTTCATGCCGGGCATATTCTTACCCCGTTTTGCTGCGGTATAGATTCCATGGATCACTG
GCTGAAACAGCGGGCGATGAAAAATCAGGTTACTGGCGCATCCCGCACCTTTGTCTGCTGCGACGACGCGAAGGTGATGG
CTTACTACTCACTGGCTTCCAGCGCTGTGACGACAAATACTGCGCCGGGTCGTTTTCGCCGCAATATGCCTGACCCGATC
CCGGTTGTGGTACTGGGTCGTCTGGCGGTGGATAAATCACTACATGGGAAAGGTGTCGGGCGGGCCCTGGTACGTGATGC
CGGGCTGCGTGTGATTCAGGTGGCGGAGACTATCGGCATTCGCGGGATGCTGGTTCACGCCCTGTCGGATGAAGCACGGG
ATTTTTACCTGCGGGTGGGGTTTGAGCCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGAGGGATTTAGTTAAT
GCCTGA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 12323.09 Da        Isoelectric Point: 9.9013

>AT239211 WP_245077106.1 NZ_CP094085:c1008641-1008330 [Helicobacter pylori]
MPNTTTEKDYTQYSEKQLFNFLNSIKTKQKRALEKLKEIQAQKQRIKKALQFKALHLTENGYTIEEEREILARAKDTKNH
LCFKSIEDFKKHCENLRFKNADD

Download         Length: 312 bp

>AT239211 NZ_LR890640:4531784-4532077 [Klebsiella pneumoniae]
ATGCCAGCCGCAAACAGCATGTCCATAAAACGCGAAACGTTAAATCTGCGCATTAAACCTGCCGAACGCGATCTTATTGA
TCGGGCGGCGAAAGCCAGAGGGAAAAACCGCACAGACTTTGTGCTGGAGGCCGCCCGCGCTGCCGCTGAGGAAGCGCTGA
TTGAGCAACGCATCATTATGGCCGATCCGCAGGCTTATCAGGAATTTCTCGCTCGTCTGGATCAGGCTCCTGCACCTAAT
GCCGCACTGCGTAAAACTATGCAGACCCCTGCGCCGTGGGAACAGGAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References