Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 568514..569084 Replicon chromosome
Accession NZ_CP094059
Organism Helicobacter pylori strain Hpfe122

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MPG39_RS02795 Protein ID WP_245081044.1
Coordinates 568812..569084 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MPG39_RS02790 Protein ID WP_075653293.1
Coordinates 568514..568825 (+) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MPG39_RS02760 (MPG39_02760) 563651..563881 + 231 WP_245056100.1 HypC/HybG/HupF family hydrogenase formation chaperone -
MPG39_RS02765 (MPG39_02765) 563900..565012 + 1113 WP_245081038.1 hydrogenase formation protein HypD -
MPG39_RS02770 (MPG39_02770) 564963..565609 - 647 Protein_528 helicase DnaB modulator -
MPG39_RS02785 (MPG39_02785) 565972..568194 + 2223 WP_245081042.1 Hop family adhesin BabA -
MPG39_RS02790 (MPG39_02790) 568514..568825 + 312 WP_075653293.1 type II toxin-antitoxin system antitoxin Antitoxin
MPG39_RS02795 (MPG39_02795) 568812..569084 + 273 WP_245081044.1 type II toxin-antitoxin system YafQ family toxin Toxin
MPG39_RS02800 (MPG39_02800) 569182..569706 - 525 WP_001120212.1 acyl-CoA thioesterase -
MPG39_RS02805 (MPG39_02805) 569848..570690 + 843 WP_096522904.1 SDR family oxidoreductase -
MPG39_RS02810 (MPG39_02810) 570683..571663 + 981 WP_000921438.1 iron ABC transporter permease -
MPG39_RS02815 (MPG39_02815) 571663..572430 + 768 WP_000242366.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10617.63 Da        Isoelectric Point: 9.7265

>T239179 WP_245081044.1 NZ_CP094059:568812-569084 [Helicobacter pylori]
MLMIETSKKFDKDLKILVKNGFDLKLLYKVVENLAKEQPLDSKYKDHPLKGVLKDFRECHLKPDLLLVYQIKKQENTLFL
VRLGSHSELF

Download         Length: 273 bp

>T239179 NZ_LR890624:3947605-3947823 [Klebsiella pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACTTCTGTCTGGAAATTTATCCGCTAA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 12359.22 Da        Isoelectric Point: 10.1678

>AT239179 WP_075653293.1 NZ_CP094059:568514-568825 [Helicobacter pylori]
MPNSPTKKDYTQYSEKQLFNFLNSIKTKQKRALEKLKEIQVQKQRIKKALQFKALHLTENGYTIEEEREILARAKDTKNH
LCFKNIEDFKKHCENLRFKNADD

Download         Length: 312 bp

>AT239179 NZ_LR890624:3947204-3947578 [Klebsiella pneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References