239123

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 4531449..4532488 Replicon chromosome
Accession NZ_CP093940
Organism Pseudomonas sp. I3-I5

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag MOP87_RS20355 Protein ID WP_242809938.1
Coordinates 4531913..4532488 (+) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag MOP87_RS20350 Protein ID WP_242809937.1
Coordinates 4531449..4531916 (+) Length 156 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MOP87_RS20330 (MOP87_20330) 4526509..4526847 - 339 WP_002555808.1 P-II family nitrogen regulator -
MOP87_RS20335 (MOP87_20335) 4527211..4527468 + 258 WP_027913405.1 accessory factor UbiK family protein -
MOP87_RS20340 (MOP87_20340) 4527504..4529513 - 2010 WP_110606422.1 DUF4034 domain-containing protein -
MOP87_RS20345 (MOP87_20345) 4529746..4531236 + 1491 WP_242809936.1 YifB family Mg chelatase-like AAA ATPase -
MOP87_RS20350 (MOP87_20350) 4531449..4531916 + 468 WP_242809937.1 helix-turn-helix domain-containing protein Antitoxin
MOP87_RS20355 (MOP87_20355) 4531913..4532488 + 576 WP_242809938.1 PIN domain-containing protein Toxin
MOP87_RS20360 (MOP87_20360) 4532669..4533445 + 777 WP_027913400.1 alpha/beta hydrolase -
MOP87_RS20365 (MOP87_20365) 4533445..4534242 + 798 WP_028686766.1 SDR family oxidoreductase -
MOP87_RS20370 (MOP87_20370) 4534371..4535282 + 912 WP_110606350.1 LysR substrate-binding domain-containing protein -
MOP87_RS20375 (MOP87_20375) 4535568..4537409 - 1842 WP_049695298.1 amidohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-115)

Antitoxin

SinI-like, DNA-binding domain

(84-130)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21840.13 Da        Isoelectric Point: 6.0738

>T239123 WP_242809938.1 NZ_CP093940:4531913-4532488 [Pseudomonas sp. I3-I5]
MRHSPFTVIYDACVLYPAPLRDLLMHLALTGVYRARGSEQIHDEWTRNVLRSRPDVSETQLYRTVGLMNRAIPDSLVNDY
EPLVQGLDLPDEDDRHVLAAAIKCGASVIVTYNLKDFPTEILKRFEIEALHPDVFLSDIWDLDHAAVLKAVQKQRAALNN
PVYSPRELLDILLKQRLPETVKHLSNHELLI

Download         Length: 576 bp

>T239123 NZ_LR890606:2402779-2404101 [Escherichia coli]
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCACCGGAGTGGTTAGCAAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CTGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCCAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTGACGTTAATACCCGAAGA
CGAAACCGTAACGCATCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGACTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCGCTAGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCACAGGAGAAGACAGCACTG
CTCAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATTAAATTACCGATTGGCGAAAT
CAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTTGATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAATGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATGCTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAATTCCAGGTCTTCCAGTGGTTGATTGGCGCAACGGACGGTCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTTTGGCGACAGCAAAGGTGCTGAGATTCCCGGAAGTGCAGATGCATGAAATCCTGAGTGACTTTGCCAGAATGATTCCA
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAAGCAATGTGTT
GAGGTTGCATGGACGGTTAAGCCGAGAATACGGTAGTAAGTGA

Antitoxin


Download         Length: 156 a.a.        Molecular weight: 17008.43 Da        Isoelectric Point: 4.9896

>AT239123 WP_242809937.1 NZ_CP093940:4531449-4531916 [Pseudomonas sp. I3-I5]
MTTADLAQAILPDEKAITAAIESSRQIAAFVSTKLDTQRIELVDEAQQRQTVELPTFALRLLGDILNELALGNTVKVVPI
HAELTTQEGADMLSVSRPHLVKLLDEGLIPHTKTGSHRRVKFTDLMAYKADRDKASQAAMDELAAQAQELNMGYQ

Download         Length: 468 bp

>AT239123 NZ_LR890606:2402513-2402779 [Escherichia coli]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTGGCGAATGCAATGAAACTGGTTCGCCAGCAAAATGGCTGGAC
GCAGAGCGAGCTGGCGAAAAAAATTGGTATTAAGCAGGCGACGATTTCCAATTTCGAAAACAACCCTGACAATACCACGC
TCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACGCTATGCGACGCGAAAAATGCCTCGCCAGAATCA
ACAGAACAGCAAAATCTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References