Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 319231..319765 Replicon chromosome
Accession NZ_CP093913
Organism Aggregatibacter actinomycetemcomitans strain 9R

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MQG38_RS01640 Protein ID WP_005545660.1
Coordinates 319231..319521 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MQG38_RS01645 Protein ID WP_005545663.1
Coordinates 319511..319765 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MQG38_RS01620 315095..316186 - 1092 WP_005545654.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
MQG38_RS01625 316483..317871 - 1389 WP_005540081.1 tRNA 5-hydroxyuridine modification protein YegQ -
MQG38_RS01630 318042..318494 - 453 WP_005540084.1 YeeE/YedE thiosulfate transporter family protein -
MQG38_RS01635 318835..319173 + 339 WP_012821089.1 cupin domain-containing protein -
MQG38_RS01640 319231..319521 - 291 WP_005545660.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MQG38_RS01645 319511..319765 - 255 WP_005545663.1 stability protein StbD Antitoxin
MQG38_RS01660 320213..320974 - 762 WP_005545665.1 DNA polymerase III subunit epsilon -
MQG38_RS01665 321042..321509 + 468 WP_005545666.1 ribonuclease HI -
MQG38_RS01670 321588..322919 - 1332 WP_005545667.1 3-phosphoshikimate 1-carboxyvinyltransferase -
MQG38_RS01675 322930..324027 - 1098 WP_005573948.1 histidinol-phosphate transaminase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11481.33 Da        Isoelectric Point: 10.6936

>T238999 WP_005545660.1 NZ_CP093913:c319521-319231 [Aggregatibacter actinomycetemcomitans]
MTYKLTFDKRALKEWEKLGDTIRQQFKNKLAERLENPRVPGDKLKGYQNLYKIKLRAAGYRLVYEVNDNQIYILVLSVGK
RNRLNAYKNAEFRQAR

Download         Length: 291 bp

>T238999 NZ_LR890562:1758836-1759168 [Klebsiella pneumoniae]
ATGGACAGAGGGGAAATCTGGCTTGTTTCACTGGATCCGATTGCTGGCCACGAGCAAAGTGGAAAACGTCCGGTACTCAT
TGTATCGAAGGCATCGTTTAACAAGCTGACCCGACTACCGGTCGTGGTTCCCGTCACCAGCGGCGGAAACTTTGCACGTA
CAGCAGGTTTCACGGTTTCACTGGAAGAGGCGGGGACCAAAACAACAGGCGTTATTCGCTGCGACCAGCCCAGGACTATC
GATATGGCGGCCCGGAAAGGCAAGCGTCTGGAACGCATACCTGACGTCGTTGTCAACGAGGTGCTTGCCAGGCTGGATGC
GATGCTGAGTTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9294.53 Da        Isoelectric Point: 3.9649

>AT238999 WP_005545663.1 NZ_CP093913:c319765-319511 [Aggregatibacter actinomycetemcomitans]
MAIHQILTQQAASITDLKRDPMGIAYASQDGAVAILNRNQPAFYCVTPALFEYFQNLVEDAELGRIAEERLATLDPIEVS
LDDL

Download         Length: 255 bp

>AT238999 NZ_LR890562:1758578-1758835 [Klebsiella pneumoniae]
ATGTATACAACTCGCCTGAAAAAGGTCGGCGGATCCATCATGCTGGCGGTTCCTCCCGCCGTGCTGAAAACGCTGGAGCT
GTCGACGGACAGCGAAGTGGGTATGACCATTGATAATGGCTGCCTGATTATTGAACCCCAGAAACGGCCCCGTTATTCGC
TTGAGGAGCTGCTGGCGCAGTGCGATCCGCACGCCGAAATGAGCGAAGAGGATCGGGAATGGATTGATGCGCCTGCGGTG
GGCAAGGAGATTCTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References