Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 1913175..1913709 Replicon chromosome
Accession NZ_CP093911
Organism Aggregatibacter actinomycetemcomitans strain 16R

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MQG37_RS09440 Protein ID WP_005545660.1
Coordinates 1913419..1913709 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MQG37_RS09435 Protein ID WP_005545663.1
Coordinates 1913175..1913429 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MQG37_RS09405 1908913..1910010 + 1098 WP_005573948.1 histidinol-phosphate transaminase -
MQG37_RS09410 1910021..1911352 + 1332 WP_005545667.1 3-phosphoshikimate 1-carboxyvinyltransferase -
MQG37_RS09415 1911431..1911898 - 468 WP_005545666.1 ribonuclease HI -
MQG37_RS09420 1911966..1912727 + 762 WP_005545665.1 DNA polymerase III subunit epsilon -
MQG37_RS09435 1913175..1913429 + 255 WP_005545663.1 stability protein StbD Antitoxin
MQG37_RS09440 1913419..1913709 + 291 WP_005545660.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MQG37_RS09445 1913767..1914105 - 339 WP_012821089.1 cupin domain-containing protein -
MQG37_RS09450 1914446..1914898 + 453 WP_005540084.1 YeeE/YedE thiosulfate transporter family protein -
MQG37_RS09455 1915069..1916457 + 1389 WP_005540081.1 tRNA 5-hydroxyuridine modification protein YegQ -
MQG37_RS09460 1916754..1917845 + 1092 WP_005545654.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11481.33 Da        Isoelectric Point: 10.6936

>T238988 WP_005545660.1 NZ_CP093911:1913419-1913709 [Aggregatibacter actinomycetemcomitans]
MTYKLTFDKRALKEWEKLGDTIRQQFKNKLAERLENPRVPGDKLKGYQNLYKIKLRAAGYRLVYEVNDNQIYILVLSVGK
RNRLNAYKNAEFRQAR

Download         Length: 291 bp

>T238988 NZ_LR890556:c3208230-3207697 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCAGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGCGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAGGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9294.53 Da        Isoelectric Point: 3.9649

>AT238988 WP_005545663.1 NZ_CP093911:1913175-1913429 [Aggregatibacter actinomycetemcomitans]
MAIHQILTQQAASITDLKRDPMGIAYASQDGAVAILNRNQPAFYCVTPALFEYFQNLVEDAELGRIAEERLATLDPIEVS
LDDL

Download         Length: 255 bp

>AT238988 NZ_LR890556:c3208507-3208241 [Klebsiella pneumoniae]
ATGCCCGCACTTAAAAAGCAGCGTATAGATTTGAGATTAACCGATGATGATAAGAGCATCATCGAGGAAGCTGCGGCAAT
TTCGAATCAGACGATTACCCAGTTTGTGGTTGCCAGTGCCTCAGAACGTGCTGCGGAAGTGATTGAGCAGCACCGCAGAA
TGGTCCTCAATGAGCAATCATGGAGCCTGGTGATGGAGGCGATTACCCAACCGCCAGCCCCGAATGATCGACTGAAACGT
GCAGCGAAGCGTCTACAAACCAGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References