Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1079968..1080503 Replicon chromosome
Accession NZ_CP093911
Organism Aggregatibacter actinomycetemcomitans strain 16R

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MQG37_RS05585 Protein ID WP_005546120.1
Coordinates 1079968..1080252 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MQG37_RS05590 Protein ID WP_005574425.1
Coordinates 1080249..1080503 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MQG37_RS05560 1075338..1077317 + 1980 WP_005546129.1 exodeoxyribonuclease V subunit alpha -
MQG37_RS05565 1077330..1077926 + 597 WP_005546127.1 class I SAM-dependent methyltransferase -
MQG37_RS05570 1078170..1078598 + 429 WP_005546126.1 50S ribosomal protein L13 -
MQG37_RS05575 1078615..1079007 + 393 WP_005546123.1 30S ribosomal protein S9 -
MQG37_RS05580 1079170..1079955 + 786 WP_005574423.1 tRNA pseudouridine(38-40) synthase TruA -
MQG37_RS05585 1079968..1080252 - 285 WP_005546120.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MQG37_RS05590 1080249..1080503 - 255 WP_005574425.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
MQG37_RS05595 1080720..1082177 - 1458 WP_005546115.1 DASS family sodium-coupled anion symporter -
MQG37_RS05600 1082407..1083186 + 780 WP_005546112.1 MmcQ/YjbR family DNA-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(18-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11175.17 Da        Isoelectric Point: 10.6072

>T238980 WP_005546120.1 NZ_CP093911:c1080252-1079968 [Aggregatibacter actinomycetemcomitans]
MSYIIEFIPSSEKEFRKLDINLRKQFIEKLKERAENPRVSSAKLHGMKDCYKIKLRNVGYHLVYQVIDERIVVKAISVGK
RDRNFVYTKAKSRL

Download         Length: 285 bp

>T238980 NZ_CP093911:c1080252-1079968 [Aggregatibacter actinomycetemcomitans]
ATGAGTTACATCATTGAGTTTATCCCATCATCTGAAAAAGAATTCCGCAAACTCGATATTAATCTGCGTAAACAATTCAT
TGAGAAATTAAAAGAACGCGCCGAAAATCCCCGAGTGTCATCCGCCAAATTACACGGCATGAAAGATTGCTATAAAATCA
AATTACGCAATGTAGGGTATCATTTGGTGTATCAGGTTATTGATGAACGCATTGTGGTCAAAGCCATCTCCGTAGGAAAA
CGCGATCGAAATTTTGTTTATACCAAAGCAAAAAGCAGGCTTTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9462.91 Da        Isoelectric Point: 4.1191

>AT238980 WP_005574425.1 NZ_CP093911:c1080503-1080249 [Aggregatibacter actinomycetemcomitans]
MTSLVLTDVVASITELKTNPMAVLREAGGKPLAILNRNEPAFYCVPPAIYEYLMELVDDAELTKIVEERQHEKSYPVDLE
DLLQ

Download         Length: 255 bp

>AT238980 NZ_CP093911:c1080503-1080249 [Aggregatibacter actinomycetemcomitans]
ATGACAAGCCTTGTTTTAACCGATGTTGTCGCCAGTATCACCGAATTAAAAACTAATCCCATGGCGGTACTTCGTGAAGC
CGGTGGAAAACCGCTGGCAATTTTAAACCGCAATGAACCCGCATTTTATTGCGTCCCACCGGCAATTTATGAATATTTGA
TGGAATTAGTCGATGATGCTGAATTGACAAAAATCGTGGAAGAACGTCAACATGAAAAAAGTTATCCTGTTGATTTAGAG
GATTTACTACAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References