Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 1910826..1911360 Replicon chromosome
Accession NZ_CP093910
Organism Aggregatibacter actinomycetemcomitans strain 27R

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MQG43_RS09405 Protein ID WP_005545660.1
Coordinates 1911070..1911360 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MQG43_RS09400 Protein ID WP_005545663.1
Coordinates 1910826..1911080 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MQG43_RS09370 1906564..1907661 + 1098 WP_258271204.1 histidinol-phosphate transaminase -
MQG43_RS09375 1907672..1909003 + 1332 WP_005545667.1 3-phosphoshikimate 1-carboxyvinyltransferase -
MQG43_RS09380 1909082..1909549 - 468 WP_005545666.1 ribonuclease HI -
MQG43_RS09385 1909617..1910378 + 762 WP_005545665.1 DNA polymerase III subunit epsilon -
MQG43_RS09400 1910826..1911080 + 255 WP_005545663.1 stability protein StbD Antitoxin
MQG43_RS09405 1911070..1911360 + 291 WP_005545660.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MQG43_RS09410 1911418..1911756 - 339 WP_012821089.1 cupin domain-containing protein -
MQG43_RS09415 1912097..1912549 + 453 WP_005540084.1 YeeE/YedE thiosulfate transporter family protein -
MQG43_RS09420 1912720..1914108 + 1389 WP_005540081.1 tRNA 5-hydroxyuridine modification protein YegQ -
MQG43_RS09425 1914405..1915496 + 1092 WP_005545654.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11481.33 Da        Isoelectric Point: 10.6936

>T238979 WP_005545660.1 NZ_CP093910:1911070-1911360 [Aggregatibacter actinomycetemcomitans]
MTYKLTFDKRALKEWEKLGDTIRQQFKNKLAERLENPRVPGDKLKGYQNLYKIKLRAAGYRLVYEVNDNQIYILVLSVGK
RNRLNAYKNAEFRQAR

Download         Length: 291 bp

>T238979 NZ_LR890554:4089532-4089750 [Klebsiella pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACCTCTGTCTGGAAATTTATCCGCTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9294.53 Da        Isoelectric Point: 3.9649

>AT238979 WP_005545663.1 NZ_CP093910:1910826-1911080 [Aggregatibacter actinomycetemcomitans]
MAIHQILTQQAASITDLKRDPMGIAYASQDGAVAILNRNQPAFYCVTPALFEYFQNLVEDAELGRIAEERLATLDPIEVS
LDDL

Download         Length: 255 bp

>AT238979 NZ_LR890554:4089131-4089505 [Klebsiella pneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References