238976

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1525422..1525957 Replicon chromosome
Accession NZ_CP093910
Organism Aggregatibacter actinomycetemcomitans strain 27R

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MQG43_RS07620 Protein ID WP_005546120.1
Coordinates 1525673..1525957 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MQG43_RS07615 Protein ID WP_005574425.1
Coordinates 1525422..1525676 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MQG43_RS07605 1522739..1523518 - 780 WP_005546112.1 MmcQ/YjbR family DNA-binding protein -
MQG43_RS07610 1523748..1525205 + 1458 WP_005546115.1 DASS family sodium-coupled anion symporter -
MQG43_RS07615 1525422..1525676 + 255 WP_005574425.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
MQG43_RS07620 1525673..1525957 + 285 WP_005546120.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MQG43_RS07625 1525970..1526755 - 786 WP_005574423.1 tRNA pseudouridine(38-40) synthase TruA -
MQG43_RS07630 1526918..1527310 - 393 WP_005546123.1 30S ribosomal protein S9 -
MQG43_RS07635 1527327..1527755 - 429 WP_005546126.1 50S ribosomal protein L13 -
MQG43_RS07640 1527999..1528595 - 597 WP_005546127.1 class I SAM-dependent methyltransferase -
MQG43_RS07645 1528608..1530587 - 1980 WP_005546129.1 exodeoxyribonuclease V subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(18-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11175.17 Da        Isoelectric Point: 10.6072

>T238976 WP_005546120.1 NZ_CP093910:1525673-1525957 [Aggregatibacter actinomycetemcomitans]
MSYIIEFIPSSEKEFRKLDINLRKQFIEKLKERAENPRVSSAKLHGMKDCYKIKLRNVGYHLVYQVIDERIVVKAISVGK
RDRNFVYTKAKSRL

Download         Length: 285 bp

>T238976 NZ_LR890554:826972-827382 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAGATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9462.91 Da        Isoelectric Point: 4.1191

>AT238976 WP_005574425.1 NZ_CP093910:1525422-1525676 [Aggregatibacter actinomycetemcomitans]
MTSLVLTDVVASITELKTNPMAVLREAGGKPLAILNRNEPAFYCVPPAIYEYLMELVDDAELTKIVEERQHEKSYPVDLE
DLLQ

Download         Length: 255 bp

>AT238976 NZ_LR890554:826725-826991 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References